You might know TMG as one of the ingredients in DoNotAge®, where it works hand in hand with NMN. But TMG, also called betaine, has plenty of benefits in its own right.

One of the most interesting is its impact on the liver. Fatty liver disease is now the most common liver condition in the developed world, affecting a huge number of people, often without them knowing. When the liver is under strain, it leaks certain markers into the blood that doctors use to measure liver damage.

Scientists wanted to see whether TMG could bring those markers back down.

The study

Researchers ran a series of human trials in people with fatty liver disease and elevated markers of liver injury.

TMG significantly reduced the key markers of liver damage in the blood. Several other measures of liver injury and scarring improved too. It also nudged "good" cholesterol in the right direction, with no rise in "bad" cholesterol. All of this came with an excellent safety record.

When the researchers compared TMG against results from other liver treatments, it held its own well.

What this means for us

This is a strong result for TMG, and a reminder that the ingredient is far more than a partner for NMN.

A healthy liver is one of the unsung heroes of healthy ageing. It filters toxins, balances your metabolism, and keeps your whole body running cleanly. Anything that helps protect it is worth paying attention to.

It's exactly why TMG earns its place in DoNotAge®, supporting your body in more ways than one.

Study reference: pmc.ncbi.nlm.nih.gov/articles/PMC13178775/