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Researchers and attendees gathered in the London conference room

London · 26 to 27 September 2026

DoNotAge®DoNotAge® Conference

The science doesn’t stop when the conference ends.

Meet the researchers. Understand the evidence. Explore what comes next in healthy aging.

Explore the talksWatch the conference film

Research. Evidence. Community.London

The conference, continued

Closer to the science. Closer to the people making it happen.

Two days in London brought researchers and communicators together to talk about how we age, what we can measure, and what you can do about it right now.

This is where those conversations live on: the human studies, the early discoveries, the hard questions, and the research our community helps support.

Discover the research we support

Partner stories

Real stories from the conference

Between the talks, we sat down with our partners and advisors to hear their stories. They include an Olympic medalist, a retired nurse, a boxing coach, therapists and creators.

FeaturingNick Engerer, Karen Faye, Marcel James, David Coldwell, Tony & Sarah Jeffries, Şükrü Özyıldız, Sima Jakutavičiūtė, Veronika Sky & Fansu Njie

Watch the interviews

The research, in their words

Big questions. Clearer understanding.

Explore the conversations by topic. Meet the speakers, read their main points and revisit the 2025 conference.

Filter talks by topic
13 conversations

Read the highlights now. Released recordings will appear here.

Cells, animals & human trials

SIRT6, DNA repair and lessons from long-lived animals

Vera Gorbunova

Professor Vera Gorbunova

University of Rochester

Vera connected the DNA repair seen in long-lived animals and people over 100 with research on DoNotAge.org SIRT6Activator®, from laboratory tests to ongoing human trials.

Main points

Three things to take away

  1. SIRT6 helps cells repair their DNA. Vera explored why especially active versions of this repair protein are linked to longer, healthier lives in some animals and people who live past 100.
  2. In older mice, SIRT6Activator® improved DNA repair, reduced frailty and extended lifespan. Two ongoing human trials in Singapore are now studying its effects in older adults.
  3. Very few fucoidan batches activated SIRT6 in Vera’s lab tests. DoNotAge.org tests every batch of SIRT6Activator® for its ability to activate this DNA repair protein.
Watch Vera & Andrei
Research profile

DNA & inflammation

The dark genome: jumping genes and inflammation

Andrei Seluanov

Professor Andrei Seluanov

University of Rochester

Andrei examined how normally silenced elements of our DNA can become active with age, and how that activity may contribute to persistent inflammation.

Main points

Three things to take away

  1. Old virus-like pieces of our DNA can switch back on as we get older. The immune system responds, which can keep low-level inflammation going.
  2. In mouse experiments, blocking these so-called jumping genes reduced inflammation and frailty, and helped the mice live longer.
  3. Andrei’s team is studying ways to keep this under control, including increasing SIRT6 activity and developing drugs that stop these DNA pieces from copying themselves.
Watch Vera & Andrei
Research profile

Ongoing human trials

Can spermidine support muscle regeneration as we age?

Søren Wilton Kudahl-Laursen

Søren Wilton Kudahl-Laursen

Aarhus University

Can DoNotAge.org Pure Spermidine help older adults repair their muscles? Søren introduced an ongoing muscle-recovery trial and a separate spermidine trial in people with heart disease.

Main points

Three things to take away

  1. Muscle stem cells repair damaged muscle, but they become less effective as we age. The study asks whether spermidine can help them work better.
  2. The muscle trial compares DoNotAge.org Pure Spermidine with a placebo in older adults. Researchers take small leg-muscle samples to examine under a microscope, alongside strength tests.
  3. A separate trial in 200 people with heart disease also uses DoNotAge.org Pure Spermidine, with heart scans and fitness tests to measure its effects.
Watch the full talk

Testing a finding

Young pig blood in an old rat: does it work?

Nicolás Cherñavsky

Nicolás Cherñavsky

Rejuvenation Science Institute · Brazil

A striking claim: tiny particles from young pig blood could rejuvenate older rats. Nicolás’s team set out to see whether they could reproduce the result.

Main points

Three things to take away

  1. The team tested tiny particles taken from young pig blood that an earlier study had linked to rejuvenation in older rats.
  2. Their first attempt did not improve the rats’ grip strength as expected.
  3. After getting missing details from the original researcher, the team planned further mouse and rat experiments to see whether the finding could be repeated.
Watch the full talk

Heart health research

Why heart disease risk can remain after treatment

Joanna Ward

Joanna Ward

University of Lincoln · PhD researcher

Joanna is investigating why some people remain at risk of heart attacks and strokes after treatment, and whether the answer lies in aging immune cells and inflammation.

Main points

Three things to take away

  1. Aging immune cells can keep inflammation going, even when blood fats are controlled. Joanna is investigating what drives this response.
  2. She compares immune cells from people with heart disease with cells from healthy donors.
  3. Samples taken before and after treatment will help the team see how inflammation changes, beyond simply lowering blood fats.
Watch the full talk
Research & funding

Human research

Quercetin and DNA repair after hard exercise

Ciara Gallardo Juan

Ciara Gallardo Juan

Ulster University · PhD research

Ciara investigated what happens to our DNA during hard exercise, and whether DoNotAge.org Pure Quercetin changes how our cells respond.

Main points

Three things to take away

  1. Ciara used large sets of biological data to investigate how exercise connects to aging and DNA repair.
  2. In a trial with 13 men, each participant completed a hard cycling test with DoNotAge.org Pure Quercetin and with a placebo at different times.
  3. The DNA-damage signal was around 60% lower with DoNotAge.org Pure Quercetin in this trial, alongside changes in DNA repair measures.
Watch the full talk

Animal research

Could we capture some of exercise’s benefits in a pill?

Constanza Cortes

Dr Constanza Cortes

University of Southern California

Exercise sends messages from our muscles to the rest of the body. Constanza is investigating whether a small protein fragment, called PS18, can reproduce some of those benefits in animal studies.

Main points

Three things to take away

  1. Working muscles release signals that can affect other parts of the body, including the brain.
  2. Her lab is investigating PS18, a small fragment of a protein, as a way to carry some of these muscle-to-brain signals.
  3. The next study compares older mice given PS18, mice exercising on a treadmill and untreated mice. The team will measure memory, frailty and metabolic health.
Watch the full talk
Research profile

Human trial results

Quercetin, blood pressure and the human trial

Lindsay BottomsJonathan Sinclair

Professor Lindsay Bottoms & Dr Jonathan Sinclair

University of Hertfordshire · University of Lancashire

Can DoNotAge.org Pure Quercetin lower blood pressure? Lindsay and Jonathan shared results from a 20-day trial in healthy adults, comparing DoNotAge.org Pure Quercetin with a placebo.

Main points

Three things to take away

  1. 40 adults joined the trial and 38 finished. Participants took either DoNotAge.org Pure Quercetin or a placebo.
  2. The DoNotAge.org Pure Quercetin group saw about a seven-point improvement in systolic blood pressure compared with the placebo group.
  3. The team also reported improvements in blood fats called triglycerides and in self-reported sleep. Other measured outcomes did not change significantly.
Watch the full talk

Funding research

Why aging research deserves more support

David Weinkove

Professor David Weinkove

Durham University · Chair, BSRA

Could studying aging help us tackle several health problems at once? David explained why this research matters, and how early funding helps promising ideas move forward.

Main points

Three things to take away

  1. David’s argument: study the biology of aging to address the shared roots of many age-related conditions.
  2. Human studies need enough participants and enough time to show whether an approach actually helps.
  3. Grants from DoNotAge.org help researchers gather the early results they need to develop larger projects.
Watch the full talk
Research profile

Cell research

Why aging cells can keep inflammation switched on

Rebecca Sumner

Dr Rebecca Sumner

King’s College London

Rebecca studied the link between cell division and our immune response, asking whether aging cells lose a natural brake on inflammation.

Main points

Three things to take away

  1. In lab tests, cells that divided faster had a weaker inflammatory response than cells that divided more slowly.
  2. The team found a natural brake on inflammation: proteins that help control cell division also help regulate the immune response.
  3. When cells grow old and stop dividing, that brake may be lost. Rebecca’s team is investigating how this could contribute to persistent inflammation.
Watch the full talk

Human research

Creatine: beyond muscles, into the brain

Sergej M. Ostojic

Professor Sergej M. Ostojic

Texas Tech University · Scientific advisor

Creatine goes far beyond the gym. Sergej’s video message and Alan’s recap explored cellular energy, brain function and new human research supported by DoNotAge.org.

Main points

Three things to take away

  1. Creatine helps cells manage their energy, which is why researchers are studying it beyond sports performance.
  2. Sergej is studying DoNotAge® Performance in human research on healthy aging, including brain function.
  3. This human trial is studying the effects of DoNotAge® Performance on aging biomarkers, including inflammation, brain function, physical performance and telomere length.
Watch the full talk

Community & research

How our community helps move research forward

Alan Graves

Alan Graves

Founder & Clinical Research Advisor · DoNotAge.org

Alan brought the science back to everyday life and explained how DoNotAge.org’s members, research funding and ingredients help scientists pursue new questions.

Main points

Three things to take away

  1. DoNotAge.org supports human studies, laboratory research and independent teams checking whether earlier findings can be repeated.
  2. That support includes PhD projects, early-career researchers and teams studying longevity ingredients.
  3. Human trials depend on consistent research ingredients and matching placebos, so scientists can make meaningful comparisons.

Recording coming soon

Research profile

2025 recap

Before London: our 2025 conference in New York

Vera GorbunovaAndrei SeluanovAndrea MaierMartin Gnoni

Vera Gorbunova, Andrei Seluanov, Andrea Maier & Martin Gnoni

DoNotAge® Conference 2025 · New York

Revisit the researchers and conversations that brought our community together in New York, from DNA repair to human trials.

Main points

Three things to take away

  1. Vera Gorbunova and Andrei Seluanov explored DNA repair, long-lived animals and jumping genes.
  2. Andrea Maier discussed clinical research and the SIRT6Activator® human trials.
  3. Martin Gnoni introduced research using DoNotAge.org Pure NMN in people living with HIV.
Watch the 2025 recap

15research projects funded through the BSRA in 2026

Your community. Real research.

Backing the questions that deserve answers.

DoNotAge.org supports longevity research through funding, research ingredients and collaborations. Behind every project is a researcher asking a specific question, and a community helping them pursue it.

Through the British Society for Research on Ageing (BSRA), DoNotAge.org funded 15 research projects in 2026. This support helps early-career researchers turn new ideas into studies, from PhD projects to human trials.

Five conference projects

Examples from our wider research support, spanning grants, study funding, research ingredients and collaborations.

  1. Human research · Ulster University

    Exercise and the DNA repair response

    Ciara Gallardo Juan is investigating what hard exercise does to our DNA, and how quercetin changes the repair response.

    PhD research support

    Explore the presentation

  2. BSRA small research grant · University of Lincoln

    Inflammation and cardiovascular disease

    Joanna Ward is studying why aging immune cells may keep inflammation going in people with heart disease, even after treatment.

    PhD project grant

    Explore the presentation

  3. Animal research · University of Southern California

    Exercise signals and the aging brain

    Constanza Cortes is investigating whether a small protein fragment can carry some of exercise’s benefits to the brain in older mice.

    Study funding

    Explore the presentation

  4. Independent replication · Brazil

    Testing a rejuvenation claim again

    An independent team in Brazil is testing a finding about young pig blood and older rats, and reporting what they find.

    Contribution to project funding

    Explore the presentation

  5. Human studies · Aarhus University

    Spermidine, muscle repair and the heart

    Human trials are using DoNotAge.org Pure Spermidine to study muscle repair in older adults and effects in people with heart disease.

    Research ingredients & placebo

    Explore the presentation

In the room

Science is a conversation.

The people, the presentations, and the moments between them. Photographs from the 2026 conference in London.

A conference presenter holding a microphone beside the lectern
Sharing the science, directly from the stage.
A speaker addresses researchers and attendees seated around tables
A shared room for science and conversation.
A presenter speaks at the lectern with a research slide projected behind
Looking closely at the evidence.
A scientific presentation discussing challenges in aging research
Big questions about the future of aging research.
A conference presenter speaking with a handheld microphone
New questions. New perspectives.
A conference presenter at the lectern in a DoNotAge.org shirt
Bringing the day’s conversations together.

For researchers

Let’s move the science forward.

Are you a researcher working on healthy aging? We’d love to hear about your project and explore how DoNotAge.org can support it.

Work with usContact the team

Select Research on the application page.

The work continues

Stay curious. Follow the evidence.

Return for released recordings and future research updates.

The questions raised in London are only the beginning.

Connect with our team