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Made to GMP & ISO9001 standards
Third-party tested, batch by batch

Pure NR Supplement

Nicotinamide Riboside supplement formulated as an NAD+ precursor, using ingredients actively used in research to support cellular energy metabolism and healthy aging pathways

Enhances Cognitive Function
Promotes Physical Resilience
Replenishes NAD
Strengthens Metabolic Function
Supports Healthy Aging

Each capsule contains 350mg NR.
Recommended daily serving: 700mg.

$45.00

In stock

Purchase options

One-time purchase

Total$45.00

Pure NR Supplement

$45.00

A closer look at Pure NR Supplement

Pure NR Supplement is part of our established individual supplement range. Review the ingredients, available format and applicable label alongside your own preferences.

Explore the linked studies alongside the product information. Keep each finding within the ingredient form, study model and conditions actually tested.

DoNotAge^® Routine and DoNotAge^® Performance provide daily sachet formats within our One-A-Day range. Individual supplements remain available for people who prefer to choose ingredients separately.

Individual supplement within our established range
Ingredient information available to review
Product amounts listed with the applicable label
Relevant research to read in context
Quality information to check for your batch

Quality, purity and clear information matter across the range. Our team can help you find the relevant product and batch information.

How It Works: The Science of Nicotinamide Riboside and NAD+ Restoration

Aging isn’t just about passing years. It’s about the steady loss of cellular energy and repair capacity. One of the most important molecules behind that process is NAD+ (nicotinamide adenine dinucleotide). It is required by every cell in your body to produce energy, repair DNA, regulate metabolism, and maintain mitochondrial function.

As we age, NAD+ levels decline significantly. By middle age, many people have lost up to half of their natural NAD+ supply. This loss has been directly linked to increased fatigue, reduced cognitive performance, slower repair, and weaker overall resilience.

That’s where Pure NR becomes essential.

1) Nicotinamide Riboside Is a Direct NAD+ Precursor

Pure NR is a bioavailable form of Vitamin B3 that converts efficiently into NAD+ through the salvage pathway. By restoring this critical coenzyme, Pure NR helps reactivate the body’s natural systems for energy production, cellular repair, and defense.

2) Pure NR Is Designed for Research and Trusted in Clinical Trials

While most NR ingredients are manufactured for the supplement market, Pure NR is produced to meet the standards of scientific research.

At DoNotAge.org, we test and verify every batch to ensure maximum purity and stability. That’s why researchers across the globe rely on our NR in active clinical studies related to aging, energy metabolism, brain health, and more.

3) NAD+ Supports Vital Systems Throughout the Body

Increasing NAD+ impacts nearly every part of your biology. Benefits seen in research include:

✔ Cellular Energy: Supports ATP production inside mitochondria to reduce fatigue and enhance vitality* ✔ Cognitive Function: Promotes brain cell metabolism and healthy neurological aging* ✔ DNA Repair: Fuels essential repair enzymes that protect genome integrity* ✔ Metabolic Balance: Helps regulate glucose metabolism and insulin sensitivity* ✔ Muscle Recovery: Enhances mitochondrial renewal in muscle tissue for strength and recovery* ✔ Healthy Inflammation Response: Supports cellular resilience under oxidative stress* ✔ Cardiovascular Support: Assists healthy blood flow and vascular function*

At DoNotAge.org, we don’t follow supplement trends. We fund and lead the research that shapes the future of health. Pure NR is developed with uncompromising standards to meet the needs of clinical researchers and those who take their health seriously.

BENEFITS OF PURE NR

✔ Replenishes NAD+: to restore energy, support repair, and protect cells from age-related decline*

✔ Enhances Brain and Metabolic Function: by supporting mitochondria and promoting balance across key systems*

✔ Promotes Physical Resilience: by fueling the mechanisms behind recovery, endurance, and stress response*

✔ Supports Healthy Aging: at the cellular level through NAD+ restoration and ongoing DNA protection*

PRODUCT DETAILS

✔ Research-Leading Purity: tested and verified for consistency and stability

✔ Highly Bioavailable Form of NR: that efficiently converts into NAD+

✔ Zero Fillers or Additives: Free from sweeteners, binders, preservatives, or artificial ingredients.*

✔ Non-GMO & Hormone-Free: Sourced from pasture-raised cattle with no added hormones or antibiotics.*

✔ Rigorously Tested In-House for Purity & Consistency: Every batch undergoes internal quality control to confirm molecular weight, peptide concentration, and absence of contaminants.*

At DoNotAge.org we prioritize health over hype, delivering ingredients used in global research, not just marketed as supplements.

Alan Graves

Founder & Clinical Research Advisor

DoNotAge.org

The Science Behind Pure NR

At DoNotAge.org, we are a Health Research Organization committed to uncovering research-led solutions that support cellular health, not mass-market trends. Our work centers around identifying and delivering the most scientifically relevant ingredients that support biological function where aging begins: inside your cells.

Pure NR is one of those solutions. As a stable, clinically trusted precursor to NAD+, Pure NR helps restore the molecule your body relies on for energy production, DNA repair, and metabolic regulation. NAD+ is involved in over 500 biological processes, and its decline has been directly linked to fatigue, cognitive changes, inflammation, and metabolic dysfunction.

We focus on verified purity, proven conversion pathways, and ongoing clinical relevance. Every batch of Pure NR is rigorously tested by our internal scientific team and manufactured to standards trusted by researchers around the world.

We’re not here to ride the wave of what's popular. We're here to build what the science supports, so your cells, and your body, can stay strong, functional, and resilient through every stage of life.

This is Pure NR. And this is what sets scientific integrity apart.

A Benchmark for NAD+ Purity

At DoNotAge.org, purity is not a promise. It is a principle.

Leading scientists and clinical researchers choose us when precision and consistency matter. That is because we do not rely on third-party claims. We verify every lot of Pure NR ourselves, ensuring it meets the highest standards of stability, bioavailability, and NAD+ conversion potential.

We control our testing protocols in-house to ensure no contaminants, binders, or fillers interfere with the efficacy of the compound. Contains only what your body needs, nothing more.

This level of transparency is why Pure NR is trusted across research institutions studying metabolic function, cognitive performance, and healthy aging. With Pure NR, scientists know exactly what they are working with: clean, stable, and consistently effective.

What the Science Says

Our approach is built on rigorous research, not recycled claims. Multiple studies show that restoring NAD+ through NR supplementation can:

✔ Enhance Mitochondrial Energy Production: Support ATP generation for improved endurance, vitality, and metabolic efficiency* ✔ Promote DNA Repair: Activate key enzymes that maintain genome integrity and combat cellular aging* ✔ Support Cognitive Health: Improve neurological resilience and protect against age-related cognitive decline* ✔ Balance Metabolism: Help regulate insulin sensitivity and glucose metabolism for long-term metabolic health* ✔ Improve Cellular Stress Response: Enhance the function of sirtuins and other longevity-related pathways that manage inflammation and oxidative stress*

A Scientific Breakthrough in Cellular Health

At DoNotAge.org, we collaborate with world-leading researchers to ensure that each ingredient we offer meets uncompromising scientific standards. Pure NR has become a core part of our mission to reverse biological decline and extend the body’s capacity for regeneration.

Research on NR and NAD+ shows meaningful potential to:

Restore essential energy metabolism and mitochondrial function
Support neurological health through enhanced cellular resilience
Promote balanced immune and inflammatory responses for healthier aging
Strengthen the body’s ability to repair and renew at the cellular level

We believe healthy aging starts at the source, by supporting the core systems that power every process in the body. That is what Pure NR is designed to do.

Pure NR is more than an ingredient. It is a research-leading solution designed to help you stay clear-minded, energized, and biologically resilient for the long term.

Join us in advancing what is possible for health and human performance. Experience the science of Pure NR today.

Alan Graves Founder & Clinical Research Advisor DoNotAge.org

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredient illustration published with pure nr

Pure NR: Cellular Energy, Repair, and Healthy Aging

At DoNotAge.org, we don’t follow trends. We lead the research. Pure NR is formulated with high-purity Nicotinamide Riboside, a clinically relevant precursor to NAD+, one of the most vital coenzymes for human health. As NAD+ levels decline with age, the body’s ability to generate energy, repair DNA, and maintain cellular function declines as well. Pure NR helps restore what aging takes away.

Trusted by global researchers and used in clinical trials, Nicotinamide Riboside is one of the most studied compounds for its impact on mitochondrial function, cellular resilience, and metabolic health.

Scientific studies show that Nicotinamide Riboside helps:

✔ Restore Cellular Energy: Boosts NAD+ levels to support mitochondrial ATP production and reduce fatigue* ✔ Support Brain Function: Enhances neuronal energy metabolism and supports cognitive clarity* ✔ Promote DNA Repair: Fuels enzymes like PARPs and sirtuins responsible for maintaining genome stability* ✔ Balance Metabolic Health: Supports glucose metabolism and insulin sensitivity across multiple systems* ✔ Support Healthy Aging: Reinforces your body’s natural repair and renewal processes as you age*

Not all NR is created equal. If you’re serious about long-term health, you deserve an ingredient that meets research standards. No fillers. No shortcuts. Just clinically trusted Nicotinamide Riboside, verified for purity and built for results.

We are committed to delivering the most scientifically advanced health solutions in the world. Pure NR is a direct reflection of that mission, clean, potent, and designed to restore your body from the inside out.

Pure NR Capsules: Clean, Research-Leading NAD+ Support

Each capsule of Pure NR contains a clinically relevant dose of Nicotinamide Riboside, a direct NAD+ precursor used in ongoing research for cellular energy, DNA repair, and metabolic health. Formulated for purity and bioavailability, without unnecessary additives.

✔ Over 98% Pure Nicotinamide Riboside: Precisely measured and verified for potency in every batch.* ✔ Non-GMO & Allergen-Free: No artificial additives, preservatives, gluten, soy, or common allergens.* ✔ Easy on the Stomach: Gentle, daily-use formulation suitable for long-term health protocols.* ✔ Vegan & Clean Label: Encapsulated in a plant-based hypromellose (HPMC) capsule with zero fillers or animal ingredients.*

If you're looking for a precision-formulated NR supplement trusted by researchers, Pure NR Capsules deliver consistent results with uncompromising purity.

Pure NR Powder: Science Leading NAD+ Support in Its Simplest Form

Each serving of Pure NR Powder delivers a concentrated dose of high-purity Nicotinamide Riboside, providing direct support for NAD+ production without capsules, fillers, or unnecessary additives. Ideal for those who prefer flexible dosing or clean-label supplementation.

✔ Over 98% Pure Nicotinamide Riboside: Free from fillers, binders, or synthetic additives.* ✔ Non-GMO & Allergen-Free: No gluten, soy, dairy, preservatives, or artificial ingredients.* ✔ Flexible, Customizable Dosing: Easily mix into water or your favorite beverage for tailored daily support.* ✔ Vegan & Clean Label: Pure powder with no encapsulation agents or animal-derived materials.*

If you're seeking uncompromising purity and precision in NAD+ support, Pure NR Powder provides a clinically relevant solution trusted by researchers and built for real biological impact.

The DoNotAge.org Quality Guarantee

This product comes with the DoNotAge.org Quality Guarantee. We proudly guarantee purity and quality from our facility to your home, no matter where you live.

✔ Produced to GMP and ISO9001 Standards: Ensuring the highest levels of manufacturing excellence.* ✔ Science-Led & Rigorously Tested: Formulated for superior effectiveness and safety.* ✔ Full Instructions Included: Your order comes with easy-to-follow guidelines for optimal results.* ✔ 100% Vegan & Clean: Free from unnecessary additives, making it suitable for all dietary preferences.*

At DoNotAge.org, we are committed to delivering science-leading solutions that empower people to live longer, healthier lives. Pure Resveratrol is part of our greater mission to advance longevity research and make cutting-edge breakthroughs accessible to all.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

World-Leading Purity and Research-Led Formulation

At DoNotAge.org, we are a Health Research Organization, not a supplement company. Our mission is to investigate, refine, and deliver the world’s most effective health compounds through science not marketing. Every ingredient we offer is selected for its clinical relevance, biological function, and verified purity.

✔ Research-Grade Nicotinamide Riboside: A direct precursor to NAD+ used in global studies on energy metabolism, DNA repair, and cellular aging* ✔ GMP and ISO9001 Certified: Manufactured under internationally recognized quality and safety standards* ✔ In-House Tested for Purity and Stability: Every batch of Pure NR is verified for identity, potency, and consistency* ✔ Clinically Studied Ingredient: Nicotinamide Riboside is widely researched for its role in mitochondrial function and metabolic health* ✔ Full Transparency: What’s on the label is exactly what’s in the capsule or powder. No fillers. No shortcuts. No compromises*

DoNotAge.org Quality Guarantee

This product comes with the DoNotAge.org Quality Guarantee, ensuring uncompromised purity and potency from our facility to your doorstep, no matter where you live.

✔ GMP & ISO9001 Certified: Manufactured under the highest standards. ✔ Third-Party Lab Tested: Verified for purity, potency, and safety. ✔ Bioavailable & Effective: Every ingredient is carefully curated for maximum absorption and longevity benefits. ✔ Vegan & Allergen-Free: No fillers, additives, or unnecessary ingredients.

Full instructions for use are included with every order.

Join us in our mission to revolutionize health and longevity, because living longer is only worth it when you're living better.

Committed to Extending Healthy Lifespan

At DoNotAge.org, our mission is simple: To extend healthy lifespan for as many people as possible.

We believe that longevity should be accessible to everyone, not just the elite. That’s why we provide the world’s purest, research-leading supplements at the lowest possible cost so more people can benefit from the latest breakthroughs in health and aging. There's a reason our longevity ingredients are actually used in world-leading studies, and by world renown longevity experts.

We work hand-in-hand with leading scientists, longevity researchers, and medical professionals to ensure that every product we offer is at the cutting edge of human health and performance. Our advisory board includes decorated longevity scientists and medical experts, ensuring that our formulations are backed by the latest research and clinical evidence.

We aren’t a supplement company, we are a global movement of over 200,000 individuals dedicated to extending and improving human health. With a growing community spanning the United States, Canada, Australia, Germany, and beyond, we are united in a shared mission: helping people live longer, healthier, and more vibrant lives.

Why We Do What We Do

Most supplement brands focus on profit. We focus on science. We are not here to maximize profits. We are here to maximize your health and longevity.

✔ Our Commitment to Research: We actively collaborate with scientists, researchers, and anti-aging experts to stay ahead of the latest breakthroughs. ✔ Making Longevity Accessible: We keep our prices as low as possible so that more people can benefit from life-extending science. ✔ No Compromises on Quality: Every batch of Pure Berberine meets the strictest testing and safety standards in the industry.

At DoNotAge.org, we are a Health Research Organization, our profits fund longevity studies and conduct our own research, ensuring that our ingredients are actually used in clinical trials.

Product & Usage

What is Pure NR, and how does it work?

Pure NR (Nicotinamide Riboside) is a research-led NAD+ precursor that helps restore levels of NAD+, a vital coenzyme involved in over 500 biological processes including cellular energy production, DNA repair, metabolic regulation, and mitochondrial function. As NAD+ declines with age, Pure NR helps replenish it at the source, supporting healthy aging at the cellular level.*

How should I take Pure NR?

Take Pure NR capsules with water. Take Pure NR Powder by mixing with water. Each scoop or capsule contains 350mg of Pure NR. Each contains a precisely measured dose of high-purity Nicotinamide Riboside designed for optimal absorption and NAD+ restoration.

What is the recommended daily dosage?

Most members take 1 to 2 capsules or scoops per day, depending on their individual needs. Consistent daily use is recommended for long-term support of NAD+ levels and overall cellular function. If unsure, start with 1 capsule or scoop of powder daily and adjust based on your health goals or guidance from a healthcare professional.

When is the best time to take Pure NR?

Pure NR can be taken at any time of day, but many members prefer taking it in the morning to support energy production throughout the day.

Is Pure NR safe to take every day?

Follow the product label and ask a qualified healthcare professional whether daily use is appropriate for you, especially if you have a medical condition or take medication.

What age should I start taking Pure NR?

Ask a qualified healthcare professional whether this product is appropriate for your age and health needs.

Quality & Purity

Is it tested for purity?

Every batch is tested for purity and verified by third-party laboratories.

Are there any fillers in Pure NR?

The capsules contain only nicotinamide riboside in a plant-based hypromellose (HPMC) shell.

Is Pure NR suitable for vegans?

This product is suitable for vegans and vegetarians.

How should I store Pure NR?

Store in a cool, dry place away from heat and direct sunlight.

Delivery

How fast do you ship once I place my order?

Orders are usually dispatched within 48 hours. See the delivery options and cost for your country at checkout before you pay.

Additional Questions

Can Pure NR be taken alongside medications?

Nicotinamide Riboside is generally well tolerated and has been studied in a range of clinical settings. However, if you are taking prescription medications or managing a medical condition, we recommend speaking with your healthcare provider before starting Pure NR.

Is Pure NR safe during pregnancy or breastfeeding?

There is limited clinical research on Nicotinamide Riboside supplementation during pregnancy or while nursing. As a precaution, please consult your healthcare provider before use.

Can I give Pure NR to my child?

Pure NR is formulated for adult use. While NR is a form of Vitamin B3, its concentrated dosing and biological activity are intended for adults. If you are considering supplementation for a child, please consult with a qualified pediatric healthcare provider.

Where can I find more research on Nicotinamide Riboside and NAD+?

You can explore clinical studies and expert-led research on NAD+ biology, mitochondrial health, and Nicotinamide Riboside through our Science & Research page. If you’d like additional peer-reviewed resources or insights from our scientific team, feel free to contact our support team. We’re here to help deepen your understanding of the science behind Pure NR.

Why buy this from us

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100% of profits fund ageing research
Your order helps pay for research into ageing. See some of the work at the DoNotAge^® Conference.
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