Product & Usage
What is Pure TMG, and how does it work?
Pure TMG (Trimethylglycine) is a methyl donor that supports the body’s methylation processes, essential for DNA repair, gene expression, detoxification, and homocysteine balance. Proper methylation is key to healthy aging, cardiovascular function, and cellular protection.
How should I take Pure TMG?
Swallow with water. Each capsule contains 500mg of Pure TMG for easy daily use.
What is the recommended daily dosage?
The typical recommended dosage for Pure TMG is 500mg to 1,000mg per day, taken as one to two capsules or scoops, depending on your health goals and dietary intake.
When is the best time to take TMG?
TMG can be taken at any time of day, with or without food. If using it alongside NMN or other longevity compounds, many prefer to take it in the morning to support methylation throughout the day.
Should I take TMG with anything else?
Yes, TMG works synergistically with:
✔ Pure NMN – Helps balance the increased methylation demand caused by NAD+ precursors.
✔ Pure Resveratrol – Supports sirtuin activity and complements DNA protection benefits.
✔ SIRT6Activator® – Further supports genomic stability and cellular resilience.
Is Pure TMG safe for long-term use?
Yes. TMG is a naturally occurring compound found in the body and in foods like beets and spinach. It has been studied for its safety and effectiveness and is well-tolerated for daily, long-term supplementation.
At what age should I consider taking TMG?
Methylation efficiency declines with age, stress, toxin exposure, and certain lifestyle factors. Most people over the age of 30 may benefit from supporting methylation with Pure TMG, especially if taking NMN or other NAD+ boosters.
Quality & Purity
What Makes Pure TMG Different?
✔ Research-Leading Purity – Formulated without fillers, additives, or unnecessary ingredients.
✔ Supports Core Biological Functions – Aids DNA repair, detoxification, and cardiovascular health through essential methylation.*
✔ Scientifically Relevant – Used by researchers and trusted in longevity science communities.
How do you ensure the purity of Pure TMG?
Every batch of Pure TMG is rigorously tested in-house and by third-party laboratories to confirm purity, potency, and safety. Certificates of analysis are available upon request.
Are There Any Fillers in Your TMG Capsules?
No. Our capsules contain only Pure TMG inside a vegan cellulose capsule, nothing else.
Where do you source your TMG from?
We work exclusively with GMP and ISO9001 certified manufacturing partners and conduct additional in-house testing to ensure every ingredient meets our strict gold standards.
Is Pure TMG suitable for vegans?
Yes! Pure TMG is 100% vegan and vegetarian-friendly, with no animal-derived ingredients.
How should I store Pure TMG?
Store in a cool, dry place, away from direct sunlight and heat. Refrigeration is not necessary, but stable storage will help preserve its integrity.
How does DoNotAge.org store TMG before shipping?
All DoNotAge.org products are stored in cool, dark, and dry conditions, in facilities that meet GMP and ISO9001 standards, ensuring product stability and purity from production to delivery.
Shipping & Subscription
How fast do you ship once I place my order?
We process orders quickly, with delivery times as follows:
- UK: Within 2 working days
- USA: 2-3 working days
- EU: 3-4 working days
- Rest of the World: 3-7 working days, depending on your location
How do I qualify for free shipping?
- USA & UK: Free shipping on orders over $50 / £50
- EU: Free shipping on orders over €200
- Worldwide: Free shipping on orders over $300
What are the benefits of the Subscribe & Save option?
✔ Automatic Deliveries – Never run out of Pure TMG again.
✔ Exclusive Discounts – Save up to 43% on every order.
✔ Priority Shipping – Get your TMG faster with priority fulfillment.
✔ Cancel Anytime – No commitments. Adjust or cancel your subscription at any time.
Please explain your Pure TMG Subscribe & Save options
We have six options. 500mg/day, 1g/day, 1.5g/day, 2g/day, 2.5g/day & 3g/day.
- Members who choose 500mg/day will receive 1 x 366 capsule containers to allow them to have 1 capsule each day for 12 months.
- Members who choose 1g/day will receive 2 x 366 capsule containers to allow them to have 2 capsules each day for 12 months.
- Members who choose 1.5g/day will receive 3 x 366 capsule containers to allow them to have 3 capsules each day for 12 months.
- Members who choose 2g/day will receive 4 x 366 capsule containers to allow them to have 4 capsules each day for 12 months.
- Members who choose 2.5g/day will receive 5 x 366 capsule containers to allow them to have 5 capsules each day for 12 months.
- Members who choose 3g/day will receive 6 x 366 capsule containers to allow them to have 6 capsules each day for 12 months.
Additional Questions
Should TMG be taken separately from medication?
TMG is generally well-tolerated and can be taken alongside most supplements and medications. However, if you are currently taking prescription medication or have a medical condition, it’s best to consult your healthcare provider before introducing TMG into your routine.
Is TMG safe to take while pregnant or nursing?
There is limited clinical research on TMG use during pregnancy or breastfeeding. As a precaution, we recommend speaking with your healthcare professional before use during these periods.
Can I give TMG to my child?
Pure TMG is formulated for adult use. If you're considering TMG supplementation for a child or adolescent, consult with a qualified pediatrician or healthcare provider.
Where can I find more research on TMG?
DoNotAge.org is committed to scientific transparency. You can explore research articles, scientific references, and detailed information about TMG and methylation support on our Science & Research page, or reach out to our support team for further guidance.