NMN and NR: what selected human studies tell us
Different NAD+ precursors, different studies. Compare the questions and results without turning separate trials into a product ranking.
DoNotAge.org · Research & community
Explore aging science, ingredient research and the people behind the work. Start with a question, follow the sources and keep the study context in view.
Different NAD+ precursors, different studies. Compare the questions and results without turning separate trials into a product ranking.

A primer on aging research: what a biological framework explains, what an experiment tests, and the questions to keep beside a headline.

As a DoNotAge.org community member, we know that you care deeply about the quality of the supplements you’re taking. You do your own research and form your own conclusions. You know that if a…

In the first piece in this series I made the case that the future of longevity supplementation is combinatorial: several well-chosen ingredients, working on different parts of aging, taken together…

A team of researchers using DoNotAge.org SIRT6Activator® to try and reverse aging are finalists in a competition to win tens of millions of dollars in funding. The XPRIZE Healthspan launched in…

On my last trip home to the United States, I was sitting at the kitchen table in my childhood home surrounded by packing boxes. My parents were getting ready to move out west after my dad retired…

Hey there, it’s Nick Engerer, strategic advisor at DoNotAge®. It feels somewhat appropriate that I write to you today, sipping on a green shaker bottle full of the latest in longevity science.…

Every day your body deals with oxidative stress: internal wear and tear caused by unstable molecules known as free radicals. Normally your defenses keep it in check, but certain environments push…

There isn't a direct link between having healthy joints and living longer. But poor joint health has a wide-reaching impact on both the quality and the length of your life. If your joints are stiff…
Heart disease remains the world's leading cause of death, and the build-up of fatty plaque inside the arteries, known as atherosclerosis, is the process behind most of it. Statins are the standard…

DoNotAge.org community members will know that creatine is more than a bodybuilding supplement. Its benefits include improved energy, recovery, and brain health. A study published this week suggests…

Longevity isn't only about eating right, exercising, and taking supplements. Some less expected factors turn out to matter, and rest is one of them. But the evidence here is more interesting, and…