Chronic sleep deprivation has been shown to:
- Impair insulin sensitivity (increasing diabetes risk)
- Disrupt the body’s natural inflammatory response
- Lower testosterone and growth hormone production (essential for repair and muscle maintenance)
- Impairs memory consolidation and emotional regulation
- Increase cortisol, the stress hormone that accelerates biological ageing
A study published in the journal Sleep found that even partial sleep restriction for just five nights resulted in significant metabolic and hormonal changes typically seen in older adults. (Spiegel et al., 1999)
The Longevity–Sleep Link: More Than Just a Theory
So, how exactly does sleep influence lifespan?
1. Cellular Repair
During deep sleep, your body produces human growth hormone, which plays a crucial role in cell repair and regeneration. This keeps your organs functioning optimally as you age.
2. Immune Function
Sleep boosts the production of cytokines, which are proteins that help fight inflammation and infection. Chronic lack of sleep suppresses this function, increasing vulnerability to disease.
3. Brain Health
Sleep clears neurotoxins and consolidates memory. Long-term sleep loss is now linked to a higher risk of neurodegenerative conditions like Alzheimer’s and Parkinson’s.
4. Telomere Length
Telomeres are the protective caps on the ends of DNA strands, but they shorten with age. A study in PLOS ONE found that poor sleep is associated with shorter telomeres, a well-established biomarker of biological ageing.
The Amino Acid That’s Helping People Sleep Better — Naturally
If you’re one of the millions who struggle to fall or stay asleep, there’s encouraging news. Alongside good sleep hygiene, one amino acid has gained attention among health researchers for its ability to enhance sleep quality without sedation.
Enter: Glycine.
What Is Glycine?
Glycine is a naturally occurring amino acid that plays a role in neurotransmission, detoxification, and collagen synthesis. But what’s particularly exciting is how glycine helps regulate body temperature, support deep sleep, and improve morning alertness, all without next-day grogginess.
Clinical research has shown that taking glycine before bed can shorten the time it takes to fall asleep, increase sleep efficiency, and reduce symptoms of fatigue the following day. (Yamadera et al., 2007)
Why DoNotAge.org’s Glycine Stands Apart
At DoNotAge.org, we do things differently.
We are a Health Research Organisation, not a supplement brand. Our mission is to lead global research on ageing and healthspan, and to provide ingredients used by leading researchers in clinical trials.
✅ No fillers, no shortcuts, no compromises
✅ Tested for purity and bioavailability
✅ Used by longevity experts around the world
✅ Supports restful sleep and cognitive clarity
Our Glycine is not just high quality, it’s part of a broader vision to advance science and give individuals the tools to live healthier, more vital lives.