The Silent Signs of Ageing You Shouldn’t Ignore
Have you ever strained to read a menu in dim lighting, or asked someone to repeat themselves for the third time, only to brush it off as “just getting older”?
You’re not alone. Vision and hearing loss are among the most common, and often most frustrating,signs of ageing. According to the World Health Organization, over 1.5 billion people live with hearing loss, and age-related vision decline is now affecting millions worldwide by their 50s and 60s. But here’s the truth: while these changes are common, they are not inevitable.
With the right knowledge and proactive care, you can protect your eyes and ears, support cellular repair, and even slow the progression of sensory decline. At the heart of this strategy is the science of senescence, inflammation, and cellular renewal, areas where Pure Fisetin from DoNotAge.org is gaining exciting traction in clinical research.
Let’s explore how these senses age, what you can do today to preserve them, and the role cellular health plays in keeping you sharp, focused, and connected for years to come.
Why Vision and Hearing Decline With Age
Our eyes and ears are complex, high-performance systems. They require constant nutrient supply, efficient cellular signalling, and immune protection to function well. As we age, several biological changes make this harder:
For the Eyes:
- Macular degeneration leads to central vision loss, often caused by inflammation and oxidative stress in retinal cells.
- Cataracts form when proteins in the eye’s lens clump together, clouding vision.
- Reduced tear production causes dry eyes and irritation.
For Hearing:
- Presbycusis (age-related hearing loss) often stems from damage to tiny hair cells in the inner ear.
- Chronic inflammation and poor circulation reduce ear health over time.
- Mitochondrial decline contributes to sensorineural damage and auditory nerve impairment.
But here’s what’s especially important: chronic inflammation and cellular senescence (zombie-like cells that no longer function but won’t die off) are now known to play a central role in this degeneration.
The Cellular Link: Senescence, Inflammation, and Sensory Health
Cells in your eyes and ears are among the most metabolically active in the body. They rely on clean, efficient energy to process light and sound in real time.
But as we age, damaged cells begin to accumulate. These senescent cells no longer divide or function properly, yet they remain in the tissue, secreting inflammatory molecules that damage surrounding cells and speed up degeneration.
This is especially harmful in the retina and cochlea, where precision and clarity are vital. Senescent cells in these areas:
- Impair mitochondrial function
- Increase local inflammation
- Promote tissue breakdown and scarring
- Interfere with nutrient flow and detoxification
This is where a new class of natural compounds called senolytics, come into the picture.
Introducing Pure Fisetin: A Natural Senolytic Used in Clinical Research
DoNotAge.org is a Health Research Organisation dedicated to advancing science through clinical trials and ingredient innovation, not a supplement brand. One of their most talked-about longevity compounds? Pure Fisetin.
Fisetin is a flavonoid found in strawberries, apples, and persimmons. But in its pure, concentrated form, it has been shown in studies to:
- Remove senescent cells from tissues
- Reduce inflammation markers linked to vision and hearing loss
- Support mitochondrial function and cellular resilience
- Protect neurons and sensory cells from oxidative stress
A 2018 study published in EBioMedicine found that fisetin selectively cleared senescent cells in mice, resulting in improved tissue function and increased lifespan. More recently, human trials are being conducted to explore fisetin’s role in age-related inflammation, cognition, and visual health.
This is not generic supplement talk. DoNotAge.org’s Pure Fisetin is:
- Used by leading researchers in clinical trials
- Verified for purity and potency
- Free from fillers or unnecessary additives
- Backed by real scientific mechanisms, not marketing claims
Used in the right context, Pure Fisetin can support the cellular environment that keeps your eyes and ears working well into your later years.