Pure Spermidine
Spermidine has the ability to activate autophagy, which is a powerful anti-ageing process that lowers systemic inflammation and preserves NAD+ levels.
Activates Autophagy
Anti-Ageing
Neuroprotector
Anti-Inflammatory
Protect telemeres
Third Party Tested
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Description
Spermidine is a polyamine known for activating autophagy. Autophagy is the process that the body uses to get rid of damaged cells and maintenance of healthy cells. Natural autophagy decreases over time, and boosting it back to youthful levels with spermidine has shown incredible results.
Studies have shown that spermidine may delay ageing in humans, support the reduction of age-related diseases, upregulate sirtuin 1, support liver health, provide anti-inflammatory benefits and support a healthy brain.
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Key Benefits
- Promotes autophagy
- Immune system support
- Protects against dementia
- Decreases development of age-related disease
- Prevents the loss of movement
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Ingredients
Each capsule contains:
8mg of Pure Spermidine
372mg of Gluten-free brown rice flour
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How it Works
Spermidine has been shown to delay ageing in humans. It is known as a geroprotector, with most benefits coming via autophagy. Spermidine is shown to:
- Potentially extend lifespan
- Improve resistance to stress
- Decrease the occurrence of age-related diseases
- Prevent the loss of movement
- Protect the heart
- Protect the cardiovascular system
- Protect the immune system
Spermidine has been shown to upregulate sirtuin 1, prevent liver damage, act as an anti-inflammatory and even promote human hair growth. It may also protect telomere length.
Spermidine may slow down human ageing, prevent age-related disorders, increase sirtuin 1, defend against liver damage, have anti-inflammatory effects, and improve cognition, all while potentially warding off diseases of the brain including dementia and Parkinson’s - according to studies.
One of spermidine’s most prominent benefits is its’ effect on the brain. Spermidine can protect your memory, boost your cognitive abilities and stop neurodegeneration.
Levels of spermidine decrease as we age, and a higher spermidine intake reduces the chance of the age-related diseases shown above.
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Subscribe & Save Explained
Please explain your Spermidine Subscribe & Save options?
We have three options. 8mg/day, 16mg/day and 24mg/day
- Members who choose 8mg/day will receive 1 x 366 capsule containers to allow them to have 1 capsule each day for 12 months.
- Members who choose 16mg/day will receive 2 x 366 capsule containers to allow them to have 2 capsules each day for 12 months.
- Members who choose 24mg/day will receive 3 x 366 capsule containers to allow them to have 3 capsules each day for 12 months.
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Frequently Asked Questions
How to take?
We recommend to take 1 capsule per day after a meal.
How much Pure Spermidine in each capsule?
8mg
Where do you source your Spermidine from?
Our Spermidine is synthetic
Is it suitable for vegans?
Yes, this is suitable for vegans.
Is it gluten free?
Yes, our Pure Spermidine is gluten free.
What should I take with Spermidine?
Most members who take Pure Spermidine also take our SIRT6 Activator, Pure NMN and Pure Omega-3 alongside the Spermidine.
How do you ensure the purity of your Pure Spermidine?
We test every batch of Pure Spermidine and only supply it to our members if the purity comes back as above 99%. Purity certificates can be provided on request.
All of our ingredients are manufactured and labelled in either USA or UK.
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Lab Data & Awards
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Delivery Information
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Reviews
100/100 - Could not be happier with this company.Well researched product and this one is clean and pure. I am happy to put this in my body.Week on and week off is how I take this.
I fast on my week off and take this with fat on non-fasting weeks.
Works very well for me.No nasties in these supplements. This is why I purchase from do not age.Gluten free Spermidine. A good one of these is so difficult to find. Please keep it this way.Brilliant - nothing more to say.My body and mind feel clear and clean. I am very grateful to do not age. thank youIn my opinion the ultimate anti-aging pill as it helps prevent brain decline. This is a real worry for me.Please make this is powder form. I really love it but hate capsules so I have to empty them.I have really been shopping around for a brand I can trust. So many of them say, 10mg of spermidine per serving, but you have to take 5 pills to get that amount.
So I like that it is 1 pill, 8mg. All sorted.I'm taking this along with Reservatrol and NMN, as current scientific opinion recommends.
Excellent delivery, price and convenience, so my favorite company for supplements.Spermidine for me is a preventative measure as opposed to a cure so I didn't feel any significant difference as I am already healthy. One positive side effect of taking this for me is I grew new hair on my scalp. This is the only thing that stopped my hair from falling. So, I’ll take it!Ive just started taking Spermadine but looking forward to receiving the benefits of fasting without the need to do fasting. :)Seems like a really good product, have started to notice a difference.Great stuff, recommend it to all ageing people who has brain fog. Also makes me feel younger.No complaints at all.60 capsules ordered every 2 months. Just wish I could get it on an auto-renew. I love it.Nice small pill with no side effects.The great thing about Spermidine is that it promotes and increases autophagy. Autophagy is absolutely necessary for a healthy body. Fasting is something that has been done for thousands of years - because it causes the body to "self eat" which means that once in autophagy, the body eats zombie cells.
Fasting isn't the easiest thing to do for many people, but the great thing about spermidine is that it promotes the autophagy even if you are not actually fasting and if you are, it ramps it up.
This is my go to and I combine with long fasts.Please do not change to a wheatgerm source. I have gluten allergy. I need to take this spermidine. Please and thank you.Purchased the product for my health.I combine this with intermittent fasting and the effects on my body and mind are amazing. Would highly recommend to anyone.I have a sensitivity to wheat so normally cannot take Spermidine. But I was so happy to find one that is not sourced from wheat!My previous brand was discontinued and finding a new brand was hard. I choose this as good dosage and well testing. There is no aftertaste or stickiness to this capsule.I have not been taking it long enough to know if it's doing what it's supposed to do. It was bought because I subscribe on YouTube to Dr. Brad Stanfield who specializes in longevity supplements. He recommended taking it, I value his opinion.The long-term science behind autophagy and cell renewal are compelling and I am hoping to see the long-lasting benefits as I continue to take this supplement. So far, no negative effects and I hope the positive will come.Nice small capsule, easy to swallow.I only take 1 every other day due to price. On the other days I make sure to eat soybeans, broccoli and mushrooms.I have been taking this product for about a year now. The immediate benefits I have seen since taking it are improvements in nail growth, skin complexion, and hair strength. These aren't the reason I take this product, but they are nice side effects!I don't normally write reviews.. but I felt really compelled due to the fact that this supplement seriously revolutionized how I feel. I'm still young and I could only imagine how someone in their later years would respond to this. My mental clarity and sleep quality are through the roof.I am convinced by the science behind this ingredient for brain health.I started taking a brand on Amazon. But was caught by an ad for donotage and their testing protocols. Well, I'm not sure what the difference is, but I love this product.The packaging had been opened and the internal seal was broken when I opened it. Customer service think it may have been inspected by customs. I returned it and they replaced it quickly for me after I provided photos.Can not say enough good things about this product. I suffered a concussion and have seen so many benefits from this product.I heard about this on the Bulletproof podcast. Seems like the next breakthrough supplement, the science behind it and benefits are very compelling!Too early to tell, but no negative effects.I have experienced a decrease in my BP. While minimal, this is good news for someone like me.
I will continue to take for 1 year and hope to see a bigger difference.I didn't really see much difference.Seems like I have more energy especially on the taxing, difficult days.
I know the science behind it is strong but I haven’t taken it long enough to say much else.It's expensive but I like it a lot : sleep a lot better - upped my energy level.This is a wonderful anti-aging supplement. People over 60 ought to take it daily. Although it is expensive, it is only 1 tablet per day. I choose this because it is tested for purity.I love this!!I have no complaints at all with donotage. Shipping was fast and the product arrived with no problem. Instruction booklet tells me all I need to know.All good. I feel an overall wellness since beginning with spermidine.Hello,
I bought this for neuroprotection to help prevent dementia.
I hope it will help.New product for me but information on the website and a couple of questions answered by the CS team helped me to see this is an important product and I take for boosted autophagyMy supplement stack is now Spermidine, NMN, TMG, Sirt6 and Creatine. Love donotage productsFeel good but will review again in 3 monthsI requested third party testing certification of the purity of this product, and others in the donotage catalogue. I was impressed at how pure these products are, and this rings true as I take Spermidine, and it has helped with my brain function in my latter years. I am much more focused and feel more concentrated when working even towards the end of the day.Fast delivery to my homeSpermidine is a funny name. I take from do not age because I have a gluten allergy and theirs is gluten free.I am a sportsman and was starting to feel very old. A friend suggested i look at this. It really has helped. I just feel like a better person. Less like an old man!Good packaging and came with a useful booklet of instructions.Great for hair! No complaintsMy grandkids think I am getting younger. I can read books clearer now and have more energy.Quick shipping to Aus. Very happy as it is a small capsule. I am not good with capsules. I sometimes empty powder out into a glass of water.I take for neuroprotection. I also have my parents taking this.Despite the stupid name, it is nothing to do with sperm thankfully! I take mainly for brain health as I have family history of Alzheimers.Such an easy addition to my day. Small capsule that I take after a healthy lunch.I have taken several biological age tests. I only take products that reduce my biological age. After adding in Spermidine, my biological age reduced. I also take NMN from donotage.Part of my very large supplement stack!This is good for my hair and daily energy. I feel much better.Thank you do no age. I love this.I had a lot of inflammatory illness. Spermidine has really helped. I have a long way to go and will continue to take this.Always part of my daily supplement stack for brain protection.I love this. I just wish I could buy in powder to make it a bit cheaper.i used to be so proud of my longer hair. then, as i started to age, it became dull and coarse, I had to cut it off. now it feels great again and i’m growing it longer againI have bought this product for my mother. I hope it will help with her declining brain functions. I trust Donotage as I take their products also.I’m quite old and this product has made me feel much younger. It’s almost like a Time Machine!Good for brain and I like that.I’m glad these capsules aren’t filled with chemicals, just the ingredientThank you do not age for this product.I can get all the way around an 18 hole course now. I feel about 10 years younger. It is amazing.Customer service team responded quickly and were really helpful. ThanksI take one of these every day after breakfast. I never miss a day.Surprisingly, this product has been a factor in my wife’s pregnancy. We had been trying to have children for a while, without success. Then I started taking Spermidine, SIRT6 Activator and NMN and it seems to have worked magic. My wife and I are expecting soon and I can’t thank Donotage enough.Good customer service, good product, well packaged, quick shipping.My skin is clearer and younger looking. Love that.My friends have noticed that I am more alert, more like my old self. I feel goodSuper fast shipping!This company makes products with no fillers, just pure stuff. This makes me feel much more trusting of the products that I am taking.super happy with this product. my skin has never felt better, and my energy levels have increased. 10/10 from me!Since I started taking this product, I have felt much more energetic throughout the day. Thank you Donotage for providing this product for me!My mother and father both had dementia. I am trying to stop myself from getting it. I hope spermidine will help.Spermidine is found in every cell of the body. Very important for autophagy. This is a very good ingredient that is well tested and high purity.Good product!Hi.
Benefits for me:
Skin and hair have improved immensely.
Sleep length and quality is better.
Thank you.
1 capsule a day. Can't really go wrong.Not sure I really feel too different since taking this. But I know the science behind it and I know it is working on a cellular level. I like that it is pure and tested by a lab that is independent.I started taking this because David Sinclair takes it. I have more clarity in my thinking and feel more focussed at work. I will continue to take it.I sleep better, I am more focussed. I love this product!I would recommend this to anyone. I have lost weight and I just feel younger since taking it.The main benefit I have seen while taking this is that my hair is growing like mad!I like the high dosage of spermidine in this capsuleI have been taking NMN and Resveratrol for two and a half years now. I feel fresh and strong and absolutely healthy. Twice a year I check my biological age. I am 55 years old and my biological clock now shows 47 years. I take Sirt 6 Activator , Fisetin, Quercetin , Sulforaboost as well as Spermidine!
Thank you for your incredible products and supporting my health!I look younger, my skin and hair continue to improve and my overall feeling of well-being is incredible and constant where I never felt like that in the past, especially not long term. Like anything else, results come from consistency and a long-term commitment and I will
Continue taking all of my current regimen of Sirt 6, Spermidine, Fisetin, Quercetin, and Apigenin, but being able to see results in just a few short months is nothing short of amazing. Thank you to the whole team you have that makes access to these supplements possible.I have long Covid and this disrupted my life for a long time. I discovered DoNotAge and specifically Resveratrol, Quercetin and Spermidine. Specifically I couldn't locate Spermidine anywhere, even though I had read all the data and firmly believed I needed to supplement with it, to get my health back. And I have my health back, as a result of these particular Do Not Age supplements!! I've added sauna use in my health routine.
As of February 2023, I'm back in the gym and all other activities.Friendly service and great products that I can trust . First class service and your supplements have made a huge difference to my health as I am seeing wonderful results thank you Donotage.
I H Owen 65 and feeling strong !I have used their products for over a year now. They are the best by a very wide margin. They are the only supplement provider in the longevity space that actually carries out research and clinical trials. I am very happy I found them.
It's very sad to see their competitors creating fake accounts and leaving dishonest reviews, too.The supplement industry is generally awash with fake products, so it’s great to have DoNotAge who regularly provide third party testing certificates to prove that their products are pure. Their prices are also very competitiveI've been taking various supplements for almost 50 years and one thing I've learned is that a very large percentage of products offered are poor quality or worse. Finding a high quality product, with good customer service, at a decent price is like finding a needle in a hay stack, especially when said product is cutting edge and difficult to manufacture, store and distribute.
With that in mind I spent a lot of time researching which company I wanted to risk my hard earned money with so I could experiment with NAD Booster. I chose DoNotAge and I am happy to report they are the needle in the haystack. Their products are excellent and customer service even better. And the cherry on top, their prices often beat the competition. I have tried several products of theirs but am particularly impressed with the NAD Booster and Spermidine. Sometimes we take a supplement, even when we don't feel any results because it's supposedly good for us, but that is not the case with DoNotAge NAD Booster and Spermadine. These products are excellent and you WILL notice a difference in how you feel.
5 Stars for DoNotAge.
