- Made to GMP & ISO9001 standards
- Third-party tested, batch by batch
Nitralis®
Extremely powerful nitric oxide booster. A human clinical trial showed more than 200% increase.
- Boosts Cellular Energy
- Enhances Cognitive Function
- Optimizes Metabolism
- Strengthens Immune Defense
- Supports Healthy Aging
- Each capsule contains 400mg Nitralis®.
- Recommended daily serving: 800mg.
Used in human clinical trials
$98.00
Everything about this product
A closer look at Nitralis®
Nitralis® is part of our established individual supplement range. Review the ingredients, available format and applicable label alongside your own preferences.
Explore the linked studies alongside the product information. Keep each finding within the ingredient form, study model and conditions actually tested.
DoNotAge® Routine and DoNotAge® Performance provide daily sachet formats within our One-A-Day range. Individual supplements remain available for people who prefer to choose ingredients separately.
How Nitralis® Works: The Science of Nitric Oxide
Nitric oxide (NO) is a vital signaling molecule that controls blood flow, oxygen delivery, and vascular health.
As we age, nitric oxide production declines significantly, leading to fatigue, slower recovery, reduced performance, and cognitive decline.
Nitralis® is scientifically formulated to restore this essential pathway, supporting your body’s ability to produce nitric oxide naturally for improved circulation and vitality.
CLINICAL RESULTS
In a randomized, placebo-controlled human study, participants taking Nitralis® for 30 days:
✔ Showed an average 226% increase in salivary nitric oxide from baseline, against negligible change on placebo ✔ Reported significant improvements in vitality, focus, and overall well-being
✔ Experienced no adverse effects, confirming excellent tolerability and safety
The trial of 85 adults aged 30 to 70 is published in the Biomedical Journal of Scientific & Technical Research (October 2025): Effect of a Proprietary Nitric Oxide Supplement (Nitralis®) on Salivary Nitric Oxide Levels: A Randomized, Placebo-Controlled Trial
BENEFITS OF NITRALIS®
✔ Boosts Circulation and Vascular Health: Encourages blood vessel relaxation and nutrient delivery*
✔ Enhances Physical Performance: Improves oxygen efficiency, stamina, and recovery*
✔ Supports Cognitive Function: Increases brain blood flow for sharper focus and mental clarity*
✔ Promotes Heart Health: Supports healthy endothelial function and balanced blood pressure*
✔ Aids Sexual Performance: Enhances nitric oxide signaling involved in arousal and blood flow*
✔ Supports Longevity: Optimizes nitric oxide bioavailability for youthful vitality and cardiovascular resilience*
The Science Behind NITRALIS®
At DoNotAge.org, we are a Health Research Organization dedicated to translating cutting-edge longevity research into real-world solutions. Nitralis® is the result of years of research and clinical evaluation, designed to help your body naturally restore one of its most vital molecules: nitric oxide.
A Clinically Proven Step Forward in Vascular Longevity
Our human clinical trial confirmed that Nitralis® increased salivary nitric oxide levels in humans by an average of 226%
Nitric oxide is essential for:
✔ Circulation and cardiovascular health
✔ Brain oxygenation and cognitive clarity
✔ Sexual performance and physical vitality
✔ Mitochondrial energy and cellular communication
With age, nitric oxide production declines. Nitralis® was developed to reactivate those pathways using research-grade, bioavailable ingredients formulated for maximum impact.
What the Science Says
Research demonstrates that supporting nitric oxide bioavailability can:
✔ Improve vascular elasticity and circulation*
✔ Enhance physical performance and recovery
✔ Support endothelial health and reduce oxidative stress*
✔ Improve cognition and reduce fatigue*
✔ Boost mood and vitality*
Nitric oxide isn’t just another molecule. It’s the life force that keeps every cell in your body communicating, oxygenated, and alive.
When nitric oxide production declines, the entire system begins to fail: circulation slows, mitochondria weaken, inflammation rises, and aging accelerates. Every chronic disease, from heart disease to cognitive decline, shares one common denominator: loss of nitric oxide.
Restoring it is not optional, it’s essential. Reigniting your body’s own nitric oxide engine will open your blood vessels, improve oxygen delivery, sharpen your mind, and allow you to reclaim youthful energy at its biological source.
The science is clear: if you fix nitric oxide, you fix the foundation of human health.
At DoNotAge.org, we are proud to set the gold standard in nitric oxide science, combining rigorous research with real-world results.
Join us in the pursuit of a longer, healthier future. Try Nitralis® today and experience the future of longevity science.
Alan Graves Founder & Clinical Research Advisor DoNotAge.org
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Nitralis®
Each serving (2 capsules, 800mg) contains:
Nitralis®: a scientifically developed, clinically proven, nitric oxide support formula designed to restore circulation, enhance oxygen delivery, and revitalize vascular performance.
Other ingredients: Hypromellose (HPMC) capsule:
✔ 100% vegan
✔ Non-GMO
✔ Free from artificial additives and preservatives
At DoNotAge.org, we don’t just follow longevity research… we lead it. Our Nitralis® is used in clinical trials as the gold standard of purity and performance. Unlike many fake supplements that hide behind fake purity certificates and diluted formulas, we independently verify every batch to ensure you get the
The DoNotAge.org Quality Guarantee
Nitralis® comes with the DoNotAge.org Quality Guarantee. We proudly guarantee purity and quality from our facility to your home, no matter where you live
Every batch of Nitralis® is tested in-house and verified for purity, potency, and bioavailability under GMP and ISO9001 standards.
✔ Third-party lab verified
✔ Bioavailable and research-grade
✔ Used in human clinical trials
✔ Suitable for daily, long-term use
At DoNotAge.org, we are committed to delivering science-leading solutions that empower people to live longer, healthier lives. Nitralis® part of our greater mission to advance longevity research and make cutting-edge breakthroughs accessible to all.

Serving size: 2 capsules. Servings per container: 183.
Amount per serving: 800mg Nitralis® (fermented beet, magnesium ascorbate, epimedium extract).
Total: 146.4g. Daily value not established.
Other ingredients: Cellulose.
Contains no artificial ingredients, wheat, gluten, yeast, soy, corn, milk or preservatives.
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
World-Leading Purity & Scientifically Verified Formulas
At DoNotAge.org, we don’t sell supplements. We advance science.
Our mission is to investigate, develop, and deliver compounds of unmatched purity and proven biological impact. Nitralis® exemplifies this mission through rigorous testing, verified results, and transparent data.
✔ Human clinical trial confirmed: used in a randomized, placebo-controlled human study with incredible results.
✔ GMP & ISO9001 Certified: Manufactured to the highest global standards for quality, safety, and consistency.
✔ Scientifically proven nitric oxide elevation: nitric oxide elevation proven in human studies.
✔ Full Label Transparency: What’s listed is what you get. No fillers, no fluff, just clean, functional ingredients your body recognizes.
At DoNotAge.org, we don’t follow trends. We define what research-led health looks like. No shortcuts. No guesswork. Just evidence-driven solutions designed for real structural results.
Longevity begins with circulation: the foundation of energy, cognition, and vitality. Nitralis® helps restore this essential system from the inside out.
DoNotAge.org Quality Guarantee
This product comes with the DoNotAge.org Quality Guarantee, ensuring uncompromised purity and potency from our facility to your doorstep, no matter where you live.
✔ GMP & ISO9001 Certified: Manufactured under the highest standards. ✔ Third-Party Lab Tested: Verified for purity, potency, and safety. ✔ Bioavailable & Effective: Every ingredient is carefully curated for maximum absorption and longevity benefits. ✔ Vegan & Allergen-Free: No fillers, additives, or unnecessary ingredients.
Full instructions for use are included with every order.
Join us in our mission to revolutionize health and longevity, because living longer is only worth it when you're living better.
Committed to Extending Healthy Lifespan
At DoNotAge.org, our mission is simple: To extend healthy lifespan for as many people as possible.
We believe that longevity should be accessible to everyone, not just the elite. That’s why we provide the world’s purest, research-leading supplements at the lowest possible cost so more people can benefit from the latest breakthroughs in health and aging. There's a reason our longevity ingredients are actually used in world-leading studies, and by world renown longevity experts.
We work hand-in-hand with leading scientists, longevity researchers, and medical professionals to ensure that every product we offer is at the cutting edge of human health and performance. Our advisory board includes decorated longevity scientists and medical experts, ensuring that our formulations are backed by the latest research and clinical evidence.
We aren’t a supplement company, we are a global movement of over 200,000 individuals dedicated to extending and improving human health. With a growing community spanning the United States, Canada, Australia, Germany, and beyond, we are united in a shared mission: helping people live longer, healthier, and more vibrant lives.
Why We Do What We Do
Most supplement brands focus on profit. We focus on science. We are not here to maximize profits. We are here to maximize your health and longevity.
✔ Our Commitment to Research: We actively collaborate with scientists, researchers, and anti-aging experts to stay ahead of the latest breakthroughs. ✔ Making Longevity Accessible: We keep our prices as low as possible so that more people can benefit from life-extending science. ✔ No Compromises on Quality: Every batch of Nitralis® meets the strictest testing and safety standards in the industry.
At DoNotAge.org, we are a Health Research Organization, our profits fund longevity studies and conduct our own research, ensuring that our ingredients are actually used in clinical trials.
Product & Usage
What is Nitralis® and how does it work?
Nitralis® helps your body naturally restore healthy nitric oxide levels, supporting circulation, oxygen delivery, and vascular health.
How should I take Nitralis®?
Take 2 capsules daily (800mg) with water, preferably in the morning or before exercise.
Can Nitralis® be taken daily?
Follow the product label and ask a qualified healthcare professional whether daily use is appropriate for you, especially if you have a medical condition or take medication.
Who should take Nitralis®?
Adults seeking to improve circulation, endurance, focus, and vascular health, particularly those aged 30 and above.
Is Nitralis® vegan and non-GMO?
Nitralis® is vegan and non-GMO.
How long before I notice results?
Individual experiences vary. Review the product information and research before choosing.
Is there a money-back guarantee?
Yes.
Quality & Purity
Are There Any Fillers in Your Nitralis® ?
The capsules contain only Nitralis® in a plant-based cellulose shell.
Is Nitralis® suitable for vegans?
This product is suitable for vegans and vegetarians.
How should I store Nitralis®?
Store in a cool, dry place away from heat and direct sunlight.
Delivery
How fast do you ship once I place my order?
Orders are usually dispatched within 48 hours. See the delivery options and cost for your country at checkout before you pay.
What do I receive when I subscribe yearly to Nitralis®?
Choose Subscribe yearly and your daily dose. Once a year you receive a 12-month supply, in containers of 366 capsules:
- 800 mg a day: 2 capsules a day, 2 containers
- 1600 mg a day: 4 capsules a day, 4 containers
- 2400 mg a day: 6 capsules a day, 6 containers
It renews once a year for the same dose at the price then.
Why buy this from us
Scientists choose our ingredients
Scientists choose DoNotAge.org ingredients for their own research. We have worked with more than 100 researchers around the world.
Money back guarantee
If you change your mind, you can return and get your money back.
100% of profits fund aging research
Your order helps pay for research into aging. See some of the work at the DoNotAge® Conference.
Free help from experts, by phone
Got a question? Our team calls every single member to see how you are doing and answer any questions you may have.
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- The Alliance for Longevity Initiatives
- ARDD
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- BSRA
- Bloodo
- Citrus Labs
- Imperial College London
- King’s College London
- Newcastle University
- Queen Mary University of London
- University of Rochester Medicine
- Teesside University
- TriHealth
- TruDiagnostic
- UNICAMP
- University of Exeter
- University of Nottingham
- University of Birmingham
- University of Edinburgh
- University of Glasgow
- University of Lincoln
- University of Oxford
- University of Southampton
- University of Arizona
- University of Central Lancashire
- University of Hertfordshire
- University of Oslo
- University of Rochester
- Washington University in Saint Louis USA
- Yong Loo Lin School of Medicine
- LifeLab1
- University of Southern California
- University of Auckland
- Ulster University
- Evandro Fang Lab
- The Clock Foundation
- Rejuvenation Science Institute
- NO-Age Network
- National University of Singapore
- University of Minnesota
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