Product & Usage
What is Pure Spermidine, and how does it work?
Pure Spermidine is a highly purified polyamine compound derived from wheat germ extract, known for its ability to activate autophagy, your body’s natural process of cellular clean-up and renewal. As spermidine levels decline with age, autophagy slows down, contributing to a buildup of damaged cellular components that can accelerate aging. Supplementing with Pure Spermidine helps restore this vital process, supporting brain health, immune function, cardiovascular resilience, and healthy aging from within.
How should I take Pure Spermidine?
Swallow with water after a meal. Each capsule contains a precise, research-led dose of Pure Spermidine for consistent daily support.
What is the recommended daily dosage?
Most members begin with 8mg of Pure Spermidine per day, as supported by current research. As always, consult with a health professional to personalise dosage based on your individual needs.
When is the best time to take Spermidine?
We recommend taking Pure Spermidine in the morning with food, aligning with your body’s natural rhythms of cellular maintenance and autophagy activation.
What should I take with Spermidine for best results?
Spermidine works well alongside other compounds that support cellular health and healthy aging:
- Pure Resveratrol – May enhance cellular protection and mitochondrial health.*
- SIRT6Activator® – Promotes DNA repair and telomere protection.*
- Ca-AKG – Supports metabolic energy, bone health, and inflammation balance.*
Is Pure Spermidine safe to take every day?
Yes. Pure Spermidine is considered safe for daily, long-term use and has been studied in both animal and human models for its potential benefits in aging, cognition, and immune health.
What age should I start taking Spermidine?
Spermidine levels naturally begin to decline in adulthood. Most people can benefit from supplementation beginning in their 30s or 40s, particularly those focused on long-term brain, heart, or immune health. While Pure Spermidine is safe for adults of any age, consult your healthcare provider if you have questions about when to begin.
Can Pure Spermidine be taken with other supplements or medications?
Pure Spermidine is generally well tolerated and can be taken alongside other supplements. However, if you are on prescription medications or managing a health condition, please consult with your healthcare professional before starting.
Is Spermidine safe during pregnancy or nursing?
Research on spermidine use during pregnancy or breastfeeding is limited. As a precaution, we recommend speaking with your healthcare provider before using Pure Spermidine if you are pregnant or nursing.
Quality & Purity
What Makes Pure Spermidine Different?
✔ Highest Purity – Sourced from premium wheat germ extract and refined to the highest purity, with no fillers or artificial ingredients.
✔ Clinically Aligned Dosage – Formulated according to research-leading standards for real-world biological impact.
✔ Activates Autophagy – Supports the body’s natural process of cellular renewal, cleanup, and repair.
✔ Used in Scientific Research – Spermidine has been the subject of extensive studies for its role in aging, cognition, and immune function.
✔ Simple and Effective – Just one daily serving delivers clean, research-leading support for cellular health and resilience.
How do you ensure the purity of Pure Spermidine?
Every batch of Pure Spermidine is rigorously tested in-house and through independent third-party labs to confirm it meets our gold purity standard. Certificates of analysis are available upon request.
Are there any fillers in your Spermidine capsules?
No. Our capsules contain only Pure Spermidine and a plant-based cellulose shell and nothing else.
Where do you source your Spermidine from?
Our Spermidine is extracted from non-GMO wheat germ, refined using low-temperature processing to maintain biological activity, and manufactured in GMP- and ISO9001-certified facilities for quality and safety.
Is Pure Spermidine suitable for vegans?
Yes. Pure Spermidine is 100% vegan and vegetarian-friendly, with no animal-derived ingredients or byproducts.
How should I store Pure Spermidine?
Store in a cool, dry place, away from direct sunlight and excess heat. Refrigeration is not required, but a temperature-controlled environment helps maintain long-term potency.
How does DoNotAge.org store Pure Spermidine before shipping?
We store all Pure Spermidine in climate-controlled, low-light environments that meet GMP and ISO9001 standards, ensuring every bottle arrives with full potency and integrity.
Shipping & Subscription
How fast do you ship once I place my order?
We process orders quickly, with delivery times as follows:
- UK: Within 2 working days
- USA: 2-3 working days
- EU: 3-4 working days
- Rest of the World: 3-7 working days, depending on your location
How do I qualify for free shipping?
- USA & UK: Free shipping on orders over $50 / £50
- EU: Free shipping on orders over €200
- Worldwide: Free shipping on orders over $300
What are the benefits of the Subscribe & Save option?
✔ Automatic Deliveries – Never run out of products again.
✔ Exclusive Discounts – Save up to 43% on every order.
✔ Priority Shipping – Get your product faster with priority fulfillment.
✔ Cancel Anytime – No commitments. Adjust or cancel your subscription at any time.
Additional Questions
Should Spermidine be taken separately from medication?
Spermidine is generally considered safe to take alongside other supplements and medications. However, if you are currently taking prescription medications or managing a medical condition, we recommend consulting with your healthcare provider before starting Pure Spermidine.
Is Spermidine safe to take while pregnant or nursing?
Research on spermidine supplementation during pregnancy or breastfeeding is currently limited. As a precaution, we advise speaking with your healthcare professional before use.
Can I give Spermidine to my child?
Pure Spermidine is formulated for adult use. While it is considered safe in general, we recommend consulting with a pediatrician before giving it to a child.
Where can I find more research on Spermidine?
We offer access to published scientific studies and educational resources related to spermidine and healthy aging. Visit our Science & Research page or contact our support team to learn more about the clinical data behind Pure Spermidine.