The word "senolytic" comes from senescence and -lytic. A senescent cell has lost its power of division and growth. A word ending with "lytic" just means to destroy. So, a senolytic is something that destroys senescent cells in the body. Senescent cells are detrimental and contribute to ageing. They increase as we get older and create a toxic micro-environment around them, leading to the creation of even more senescent cells.
There are several ways to reduce senescent cells. Fasting has been shown to be one of the most powerful methods, particularly extended fasts, typically lasting 4 or 5 days twice per year. It's essential to seek medical advice before undertaking extended fasts for correct supervision and to avoid negative outcomes. Ongoing intermittent fasting is also beneficial, and DoNotAge recommends intermittent fasting throughout the year for its numerous longevity benefits. Many people find it easiest to have a four-hour eating window each day, commonly referred to as 20:4.
Exercise is another effective way to reduce senescent cells. Studies have proven its positive effects. A 2016 study shows that exercise prevents both the accumulation of senescent cells and the expression of cells associated with causing senescence and inflammation.
In the latest studies, certain supplements have demonstrated a senolytic effect greater than the methods mentioned above. The most powerful senolytic supplement is fisetin, a plant flavonoid found naturally in certain foods. The highest concentration of fisetin in food is found in strawberries. Unfortunately, to get enough fisetin to activate its senolytic qualities, one would need to eat hundreds and hundreds of strawberries every day. As is often the case with products, the best ingredients for your body have been found and concentrated into easy-to-consume capsules. Nature provides the answers, and these supplements help enhance their benefits!
In the realm of natural remedies, few substances possess the multifaceted potency of Berberine. Derived from various plants like barberry, Oregon grape, and tree turmeric, Berberine has been revered for
Join us for an exclusive interview with Kristian Morgan, the world-record-breaking ultra-marathon runner, as he shares insights into his phenomenal journey on the Appalachian Trail.
Welcome to our latest blog post, where we delve into the realm of longevity, scientific innovation, and youthful living. Join us as we explore the groundbreaking Professor Vera Gorbunova Bundle, a revolutionary
Discover the key to unlocking optimal health in our latest blog as we delve into the extraordinary benefits of Pure CoQ10. Join us as we explore its potency, purity, and why it stands out in a saturated
DoNotAge.org are on a mission to ensure that everyone has the chance to experience a life filled with vitality and longevity. This blog will discuss our