As a DoNotAge.org community member, we know that you care deeply about the quality of the supplements you’re taking.
You do your own research and form your own conclusions. You know that if a company tells you they have a powerful ingredient but doesn't tell you what’s in it, you should stop giving them the time of day. If a company tells you what’s in their supplement but doesn’t tell you how much, you know that probably means it’s underdosed. This scrutiny is important and we would expect nothing less.
Here’s a look at every ingredient that goes into DoNotAge® (get ready - this is going to be a long blog!)
SIRT6Activator® - 1600mg
SIRT6Activator® is the most popular single ingredient DoNotAge.org provides. It is the only verified activator of Sirtuin6 - the longevity gene - in the world. SIRT6Activator® promotes DNA repair, inflammation control, and more.
NMN - 1000mg
One of the most important longevity ingredients available today. NMN stimulates NAD+ production in the cells, fuelling cellular reproduction, energy, and DNA maintenance.
Many popular ‘longevity drinks’ contain just a tiny amount of NMN as a cost saving measure. We are proud to provide you with a clinically effective dose of the purest NMN on the market!
TMG - 1000mg
TMG works hand in hand with NMN. When your body converts NMN into NAD, it uses up methyl groups. TMG replenishes those methyl groups. Without it, boosting NAD can actually deplete your methylation capacity, which affects everything from detoxification to gene expression.
We include TMG at a full dose of 1000mg because it needs to be there.
Glycine - 2000mg
Glycine is an amino acid that your body uses for collagen production and detoxification. It improves sleep, supports the liver's ability to clear toxins, and protects cells from oxidative stress. It's also involved in the production of glutathione, which is your body's master antioxidant.
Ca-AKG - 800mg
Calcium Alpha-ketoglutarate is crucial for cellular energy production. It’s been shown to extend healthspan and is currently the subject of a study related to reducing biological age.
AKG activates the krebs cycle, which is how your cells produce energy. Using the calcium-bound form makes it stable and improves absorption.
trans-Resveratrol - 500mg
Resveratrol activates Sirtuin 1, a protein involved in supporting heart health and reducing inflammation.
A recent meta-analysis of 20 years of clinical research found that resveratrol benefits human health.
Nitralis® - 400mg
Nitralis® has been clinically proven to increase nitric oxide, leading to increased performance and better vascular health.
We developed Nitralis® because other nitric oxide boosters on the market were getting the science wrong. Since launching in December, it’s been one of our most popular ingredients.
Quercetin - 400mg
Quercetin is a powerful flavonoid with strong anti-inflammatory properties. It also supports your immune system and helps with allergy relief.
Quercetin also enhances the effectiveness of resveratrol.
Vitamin D3 (5000IU), K2 (120µg), and Magnesium (250mg)
We group these ingredients together because they need each other to work properly.
Most people are deficient in Vitamin D, a crucial vitamin involved in immune function, mood regulation, bone health, and much more. What most people don’t know is that Vitamin D supplements don’t work without adequate magnesium. Magnesium converts Vitamin D into its active form, which is why we combine these ingredients.
Beyond making Vitamin D work, magnesium is important for sleep, muscle function, and nervous system regulation.
Vitamin K2 directs calcium to where it needs to go (your bones and teeth). When you take Vitamin D, it produces calcium which can end up in your blood vessels. Vitamin K2 ensures this calcium goes to the right place
SulforaBoost® - 230mg
Another DoNotAge.org exclusive! SulforaBoost® is the premium sulforaphane supplement. It combines glucoraphanin and myrosinase, the 2 things your body needs to create sulforaphane in the gut. Sulforaphane is a hugely powerful antioxidant that supports detoxification, reduces inflammation, and protects your cells.
High Molecular Weight Hyaluronic Acid - 200mg
High molecular weight hyaluronic acid has been proven to improve skin hydration, reduce wrinkles, and support joint health.
We use the high molecular weight variety of hyaluronic acid because the other kind (used in most supermarket products) actually promotes inflammation.
CoQ10 - 200mg
CoQ10 is essential for mitochondrial energy production; something every cell in your body relies on.
Spermidine - 8mg
The final ingredient. Spermidine activates autophagy: the process of cleaning out damaged cells and replacing them with new ones. This process slows down as we age and spermidine helps us speed it back up!
15 ingredients, 12 hallmarks of ageing, 1 daily supplement.
Ageing isn’t caused by just one thing. It’s multiple processes breaking down at the same time.
NAD levels drop, inflammation increases, your joints start to hurt, autophagy slows down, and so on.
DoNotAge® is unique because it tackles all hallmarks of ageing with a proper dose of clinically proven ingredients.
It’s the longevity solution you deserve.
