Pure TMG
TMG, also known as Trimethylglycine, is a molecule that comes from the amino acid glycine and is important for various bodily functions. It is used as a methyl donor for the human body.
Methyl Donor
Anti-Ageing
Anti-inflammatory
Protects Liver
Heart Health
Third Party Tested
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Description
TMG is a powerful methylation agent that influences gene expression, cell repair, and the removal of harmful toxins from the body. Its’ anti-inflammatory properties and ability to support various bodily functions contribute to its diverse health benefits.
Studies
- Studies have explored the effects of TMG supplementation on body composition, performance, and muscle endurance in strength-trained individuals, demonstrating its potential to enhance physical capabilities. (Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651845/)
- Research has investigated the role of TMG in protecting the liver from alcohol-induced harm and reducing the progression of non-alcoholic fatty liver disease. (Reference:https://pubmed.ncbi.nlm.nih.gov/28849079/)
- Investigations into TMG’s cognitive benefits have highlighted its’ ability to improve memory problems, maintain nerve cell connections, and reduce harmful chemical reactions in the brain.
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Key Benefits
One of the Pure TMG supplement’s health benefits is produced during a process called methylation. Methylation influences gene expression, fixes cells, and removes harmful toxins in the body.
1. Enhanced Heart Health
TMG can improve heart health by keeping a substance called homocysteine at the right level in your blood. Having too much of it can be bad for your health, especially for your heart. So, by using TMG, you might be able to keep your heart in better shape.
2. Liver Protection
TMG can shield the liver from the harmful side effects of alcohol by managing fat and energy levels, reducing cell changes, and maintaining proper gene and protein activity. It has also been found to help reduce non-alcoholic steatohepatitis, and advanced form of non-alcoholic fatty liver disease.
Reference:
https://pubmed.ncbi.nlm.nih.gov/28849079/
https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash
3. Cognitive Support
TMG plays a role in protecting brain cells from stress, supporting neurotransmitter production, and enhancing cognitive functions like memory, focus, and problem solving.
4. Physical Benefits
TMG supplements can improve muscle endurance.
In a study, it was found that those who took TMG supplements performed significantly better whilst exercising than those who didn’t.
The study assessed 2 groups of healthy males. Participants had to perform a vertical jump, a bench press and a squat of 90% of the person’s 1 rep max, and as many reps as possible with 75% of their 1 rep max on bench press as well as squats. On day 2 participants performed two 30-seconds Wingate anaerobic power tests (WAnT), each test separated by a 5-minute active rest.
Reference:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651845/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844502/
5. Reduced Risk of Dementia
TMG has been shown to improve memory problems caused by restricted blood flow to the brain, maintain proper functioning of nerve cell connections, reduce harmful chemical reactions caused by stress, and increase protective substances in the brain.
Reference:
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Ingredients
- 500 mg trimethylglycine
- Vegetable cellulose capsule
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How it Works
We recommend TMG, particularly for those that take NMN. TMG, or trimethylglycine, acts as a methyl donor to ensure you get the full benefit from your NMN.
TMG has anti-inflammatory properties, can boost your exercise performance and protects both your liver and your heart.
Studies have shown that TMG can also:
- Reduce fatigue.
- Boost your body’s production of proteins.
- Increase the synthesis of creatine.
Creatine is a compound that helps to provide more energy to the muscle cells in your body. By increasing the production of this compound, you will be able to reduce physical exhaustion and help support your muscle growth.
Useful links:
- Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women | The Journal of Nutrition | Oxford Academic
- Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism
- Effect of betaine supplementation on power performance and fatigue – PMC
- Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
- Article Betaine, ethanol, and the liver: A review
- Effects of betaine on body composition, performance, and homocysteine thiolactone – PMC
- Betaine in Inflammation: Mechanistic Aspects and Applications – PMC
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Subscribe & Save Explained
We have six options. 500mg/day, 1g/day, 1.5g/day, 2g/day, 2.5g/day & 3g/day.
- Members who choose 500mg/day will receive 1 x 366 capsule containers to allow them to have 1 capsule each day for 12 months.
- Members who choose 1g/day will receive 2 x 366 capsule containers to allow them to have 2 capsules each day for 12 months.
- Members who choose 1.5g/day will receive 3 x 366 capsule containers to allow them to have 3 capsules each day for 12 months.
- Members who choose 2g/day will receive 4 x 366 capsule containers to allow them to have 4 capsules each day for 12 months.
- Members who choose 2.5g/day will receive 5 x 366 capsule containers to allow them to have 5 capsules each day for 12 months.
- Members who choose 3g/day will receive 6 x 366 capsule containers to allow them to have 6 capsules each day for 12 months.
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Frequently Asked Questions
How to take?
TMG contains glycine and this can aid sleep. So most members take it around 30mins before bed. However, if it fits into your supplement schedule better to take it at a different time, this is fine.
How much Pure TMG in each capsule?
500mg of Pure TMG in each capsule
What is the recommended daily dosage for Pure TMG?
We recommend a daily dosage of at least 1g per day. If you are taking Pure NMN alongside Pure TMG, then we recommend to take on a 1:1 basis.
Is it suitable for vegans?
Yes, this is suitable for vegans.
What should I take with TMG?
Pure TMG helps Pure NMN absorb better in the body, so the majority of our members take Pure NMN and Pure TMG together.
How do you store my TMG once it is manufactured?
Our products are manufactured and stored in cool, dark and dry environments. All of our products are produced to GMP and ISO9001 standards.
How should I store my TMG?
TMG is best stored in a cool, dry cupboard. Keep it away from direct sunlight and extreme heat.
How do you ensure the purity of your Pure TMG?
We test every batch of Pure TMG and only supply it to our members if the purity comes back as above 99%. Purity certificates can be provided on request.
All of our ingredients are manufactured and labelled in either USA or UK.
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Lab Data & Awards
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Delivery Information
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Reviews
So far so good. I take this with NMNGreat!Only works well in combination with NMNSo far, all deliveries are good, clean, no unwanted side effects.I love this TMG.
Works perfectly with NMN and keep my energy quite constant, specially when I'm low or I don't sleep well/enough.
Thanks, I'll order more!Excellent supplement if you have the MTHFR gene. I take two of these first thing in the morning on an empty stomach.Taking alongside NMN, feeling much more awake and ready for the day! Early days but pleased so far.Happy with my purchase and no horrid additives.Good quality, vegan and third party tested.High quality, purity and value for moneyThis is a good quality supplement, without unnecessary additives ... no magnesium stearate!I heard about this product on YouTube when researching supplements such as NMN. It explains that this supplement runs well alongside NMN. So far, so goodThis seems an excellent product with no unnecessary additives.
Easy to take, no adverse effects on the digestive system. Looking forward to seeing the resultsAs part of my health regime plan I came across TMG from Do Not Age and use it alongside NMM as they work well together.It works well for me.I started taking TMG after reading The Homocysteine Solution by Patrick Holford. Lowering your homocysteine levels brings so many health benefits and this is what TMG does. I buy other DNA supplements, like the fact that they are made in the UK and 3rd party tested.Not a noticeable difference , but I’m taking glynac and nnm so hoping this is doing some background workI've been trying to improve my methylation for a while now, and have become quite familiar with being under methylated or over, adding TMG has smoothed out the days methylation and given a much improved mood as well, presumably because the other loop in the methylation process is now more active.Love this company, third party tested, what they say is in it is in it! No added fillers or bulking agents and purity. TMG is so good for methylation and liver function would definitely recommend!I actually use 7-8 products of theirs on a daily basis. As a Personal Trainer and general fitness fanatic, my performance and recovery is key. I trust this brand and their range to help provide me the edge and support I’m looking for. Their customer service is also excellent (thank you Charlie)!I have got this and NMN. I am happy with these supplements.I bought this but was a bit skeptical initially even though I had started using it. It’s a week now and I feel I made the right choice. TMG helps with methylation, lowers homocysteine , supports the liver and lungs.( do your research on this good stuff) I can feel some difference already, will definitely buy again.No upset stomach good purity TMG 500mg.
Best of all, it's third party tested.I haven't noticed any difference yet. Hopefully it will comeI've got this on a subscription and have just received my fourth bottle. I take two per day, so have been using this for almost a year. I like the fact it's third party tested , batch numbered and produced under GMP (which is pretty standard, but better than nothing). This seems to be consistently the best value source of reliable quality TMG/betaine. Recommended. Examine.com has a good write up of the science and applications of TMG.I like that these are 3rd party tested, made in the uk and gmp certified. They also don't contain any nasty ingredients.TMG wont be changing your life, but if you take an NAD booster like NMN or NR, this is a necessity.$20 to improve your heath.2 capsules of TMG with 2 capsules of NMN as soon as I wake up. Been taking this for about a year now and no complaints and energy levels are great.
I am a happy customer and will be ordering this for the rest of my life.TMG -
My review on this is simple really.
I take it at night. In a 1 to 1 ratio with my NMN and it helps with absorption. It won't blow your mind, but for the price, it is great!No complaints. Not really sure what it does, but I take it because I love my NMN so much.No more afternoon slumps for me, thanks to TMG combined with NRTMG has been a solid addition to my health routine.
Really love the pure quality of this TMG supplement. Thank you donotage.Been feeling less stressed since starting this. I'm not even sure if that is a side effect really! But that's how I feel.
It's been a month, and the results are evident. I take NMN, TMG, collagen and CoQ10. I notice the difference, my friends and family notice, I am very happy
NMN and TMG really helped with my mood swings and overall mental health.My memory and focus have improved since taking this.NMN and TMG combo is now a staple in my morning routine.I was on the fence, but now I'm fully on board with TMG.The purity and potency of this product is top-notch.A friend recommended TMG and NMN , and I can't thank her enough. I love it.Great energy boost, quality and experience with this product!Fantastic product,66 year old male up at 4.30 am in gym then ten hours work. Sleeping loads better. I take with NR from do not age also.First class product and delivery time.Excellent supplement that goes well with CoQ10, helpful for the heart. Prompt delivery and no added nasties.TMG along with MNM: in my experience works well together. I have found that I am less tired plus I changed my diet and eat less meat. I am 59 years old.Great product highly recommendedGreat product energising for a 68 year old, working 10 hours a day and hour in gymI'm absolutely thrilled with my purchase of the TMG tablets from do not age. They are of excellent quality and have greatly contributed to my wellness regimen. I highly recommend them!5 months of taking TMG along with NMN now and its made such a difference to my lifestyle whilst being at a great affordable priceI will take anything that says it makes me feel better, most of them do nothing, just cornstarch in a capsule, but Donotages products are good to take because they actually work and there are purity certificates to back that upI wasn’t sure about much of the science surrounding supplementation, but the customer serveuse team were really knowledgeable and helped me to find the right products. I take NMN, TMG, Sirt6 and SureSleepI contacted my doctor after suffering with IBS for some time. The recommendation was the usual, avoid gluten, don’t eat spicy foods, etc. I followed up with a specialist, saying my IBS could be a symptom of under-methylation. I was told to take TMG, and this product has reduced my pain. Thank you donotageGreat product, and for saying it came from the UK, delivery was not too longfor a product so useful, this is great value for moneythis product must be taken with nmn, otherwise your nmn wont be as effektiveNoticed a profound increase in energy and overall liveliness throughout the day, especially in the morning when I used to feel quite groggyImpressed with purity of this productThis product is now part of my supplement stack. Everyone told me to take it alongside my NR and I was reluctant to begin with but now it is a mainstay in my daily routineI like the capsules but some people might not be able to swallow the capsules, so a powder product might be an idea…I use this product alongside Sirt6 to aid my brain fogginessMy experience with Donotage has been good. No need to contact anyone in customer service. My parcel came pretty quickly and was extactly what I ordered.Good products.You should always take Tmg if you take Nmn or Nr.Very happy with my TMG.
Came well packed up with instructions.
All good!Thank you do not age for providing us all with good pure products. It is important to know what you are putting in your body.My stack:
NMN
TMG
SIRT 6 Activator
Hyaluronic Acid
CollagensSuper fast delivery. Good packaging. Capsules aren't too big. I take TMG because I also take NMN.I added this to my routine with NMN. It actually really improved my sleep. I did not even know that could happen with this product!I do not like capsules, wish you would make a powder. I empty the powder out and take with a drink.I started taking nmn around 1 year ago. It was great. After a little while I started to get a bit tired, like nmn wasn't working as well. So customer service suggested I try adding in tmg. It has rejuvenated me and I feel the energy from nmn again.TMG & NMN comboNo complaints. Good price. Order with nmn.Was told I need to take TMG to help with methylation. I take in evening and NR in morning.Take with my NMN to increase efficacy of NMNi emailed the customer service team and they were so helpful in finding me the right product for me and my husband.I love this product. I wish I could afford the other Donotage productsI work out often and I have seen an increase in the size of my muscles. This is great for me because I never saw this advertised as a benefit. Thanks Donotage!I originally thought that Donotage were just trying to upsell me TMG. However after taking NMN without TMG and with TMG, I can say there is a remarkable difference.i always thought supplements were a waste of money. I take NMN and tmg together and I couldn’t have been more wrong. They are greatFor the price, I find this great value for moneyI bought this for my elderly grandmother who was struggling with her brain functions. After taking for 2;3 months, we have seen a hugee improvement in her brain sharpness and obverall stabilityI do many sports, and struggled with fatigue. taking this product helped me to combat my tiredness.I have experienced no side effects since taking this productI have felt much better since taking TMG alongside NMN. I always felt groggy and ill before, now I feel energetic and healthyAlways take TMG with my NMN :)I was a bit sceptical about trying a different brand of TMG than I'm used to buying from my usual supplier but since trying Donotage's TMG I haven't looked back! Since trying their TMG I have now changed my current supplier completely I am taking both NMN & TMG from Donotage. These have both improved my NAD levels massively as I also ordered 2 NAD Test Kits along with my first pot of TMG to check my levels before and after 3 months. I have now ordered the TMG 366 Capsules and the NMN 366 Capsules and cannot wait to continue my longevity journey with DoNotAge!I started my new found healthy journey with a starter pack and haven't looked back since. TMG along with NMN, sirt6 and resveratrol have me feeling like a new person the difference in my energy levels and appearance alongside my overall health are down to the fantastic work put in by the donotage team so thank you!!Always take this alongside NMN, Sirt 6 Activator and Apigenin. Wouldn't be without any of them, even when travellingI love this productA couple of years back I was on the verge of turning 50, suffering from some long covid symptoms, brain fog and the long term effects of a chronic condition (and the major surgery that went with it a couple of years earlier).
NMN and TMG seemed to slowly turn things around - and now about 18 months on I feel like I've reclaimed some of the vim and vigor I felt back in my 30s. I've since added more of DoNotAge's products to the list. As a result, each day I near bounce out of bed with enthusiasm for my mentally demanding work and physically demanding hobbies. Gone are all of the aches and pains I used to feel.Two years ago, my father's health took a sharp decline, leaving my mother with little hope for his future. In a bid to improve his well-being, I turned to DoNotAge and purchased NMN, Resveratrol, and TMG supplements for him. Over the subsequent months, we witnessed a remarkable transformation in his health and overall quality of life. Just six months later, he was moving with ease and newfound vitality.
I firmly believe that if it weren't for DoNotAge, my father wouldn't be with us today. My heartfelt thanks go out to you for this incredible transformation!I’ve been taking NMN, TMG, Resveratrol, Fisetin and Berberine. I certainly noticed the boost in my immune system. I am a licensed Aesthetician and provide and do on myself lots of overall health treatments. Last month I was able to do an IPL (Intense Pulsed Light) treatment for my dark spots. Usually the redness that I usually get from treatment lasts for 2 days. This time my redness went down significantly same day and next day wasn’t existent. I happen to swell as well on my face when do this treatment, yet I didn’t swell this timeI have only been taking DoNotAge supplements for only two months. I started with the beauty bundle, and I added NMN, TMG, Resveratrol, Sir6Activator and I am definitely hooked for good. I do not only feel youthful, I look better.I am a 60 year old (155 lbs) fitness enthusiast. Have noticed in decline in my stamina at the gym over the last few years due to age. After 2 days of Pure NMN (1 pill/day) taken with 1 Pure TMG, I experienced a noticeable increase in energy and stamina (ie: more reps and heavier weights). Recovery appears to be better as well. I can not comment on its sleep affects as I take the pills in the morning about an hour before the gym)". I would recommend others give this a tryI had suffered from chronic pain, extreme fatigue (and hence inability to exercise), hypothyroidism, and other conditions for most of my adult life.
I started with your NMN powder and TMG. I was so excited I had my 83-year old mom get on the bandwagon too.
I now have more energy, vitality and for the first time since I was a teenager, I had the ENERGY and DESIRE to exercise. I had always wanted to exercise in my adult life but had no energy to. I only had enough to get through the day. With your supplements I now look forward to long walks, HIIT workouts, trampoline time and playing with my teenagers. These supplements have made all the difference.
I've been so grateful for your products, I have shared with othersI could not previously get past daily fatigue and ongoing inflammation throughout my body. First, I started with DoNotAge's NMN and TMG. Since Day-1, I now have energy all day without any dips! It is amazing to live life fully awake. Second, I added Resveratrol and Berberine to experiment with resolving the full body inflammation. Within 48-hours, the inflammation resolved by 50%. I look forward to continuing to heal this aspect. I wish I found DoNotAge sooner as I have consistently put in a lot of effort to solve these mystery health issues. Life is so much easier with daily energy and minimal inflammation!The products I purchased: NMN, CA-AKG, TMG, Vit-D, Collagen, sleeping aid, Hyaluronic Acid, Sirt-6, Sulforaboost, Resveratrol, Spermidine, Berberine and others. My vit D levels usually low, but after taking the DoNotAge supplement, I took a blood test and my levels increased.Every time I order from Do Not Age
It arrives promptly
The customer service is outstanding and all of my many questions are answered extensively
It is certainly too early to tell what effects the suite of products will have as im just getting started
But I have a very very high degree of confidence in this company as it is recommended by so many researchers in the anti aging community
And their products are ALL backed by very stringent science abd quality control for purity,shelf life and clinically recommended dosage
I am also very excited to be on board with a company that puts health far far above profit
Do Not Age is primarily interested in providing the highest quality at the lowest possible priceI have been a customer of DNA now for over 6 months, started off with NAD Booster, resveratrol, tmg and have been adding to my stack as time and cash have become available. I have lost at least 28lbs of unwanted fat, increased my stamina, mood is enhanced and an exercise regime has been built from zero. At 67 I feel as fit as I did in my 40s and I feel it will continue to improve. More than satisfied with all their products and would not hesitate to recommend.I have been using their products for a while now, and I couldn't be happier. I recently had to get my driver's license renewed, and I couldn't believe it. I actually look younger in my new picture than I did in my previous license photo (which was taken 6 years ago!!). I've used the same products from other companies in the past but I have never seen results like this this until switching to DoNotAge. I look younger, feel better, have been losing body fat, the list goes on and on. They are the best and they now have a customer for life.I love this company. I have been using their products now for 1 year and I am really impressed. I have bought NAD Booster, Resveratrol, TMG, CaAKG, Fisetin, and more . I look and feel much younger and continue to get great benefits. The customer service is awesome. Always flexible, never had a problem and they go out of their way to be helpful.I have been using Resveratrol, NAD Booster, TMG, Quercetin and Apigenin for about a year. DoNotAge customer service has been excellent throughout. All queries have been answered promptly.
The main purpose of using supplements has been to combat the affects of ageing. It appears to be helping sugar levels and blood pressure; both caused by diabetes.
Just come back to restock as ran out.I have been taking Do Not Age supplements for around the last 3 years and I must say it was a very smart decision for my health and well being.
I feel, and am performing rather better than 4 years ago.
I am a runner and just noticed (the last 2 months), with a bit of delight I must say, that during my last 5 races including 3 parkruns, 1 full marathon and a 10 km race, I finished number 1 in my age category (70 to 74) in all of them, which is quite unusual for me as I am just a fun run amateur.
So my opinion is that the DNA supplements are doing a good job in my body. I am mainly taking NAD Booster, SIRT6 Activator, TMG, Ca-AKG plus a few more…
And this is only the start of the good news, as there is something that is unbeaten at Do Not Age and this is the Customer Service...
Many thanks and best wishes to this company, Alan Graves their CEO and the great team!I am completely new to these supplements and have emailed donotage many times and always had a response to my emails trying to help me. I was sceptical about whether I would feel any difference taking these supplements but have been feeling so drained tired and no energy it was worth a go and I cannot explain the difference I feel on the nmn and tmg and other supplements I am full of energy all day and would highly recommend donotage as a very reputable company and excellent supplements
